BACKGROUND Coronary heart disease (CHD) risk increases with age; yet lipid-lowering therapies are significantly under-utilized in patients > 65 years. The objective was to evaluate the safety and efficacy of lipid-lowering therapies in older patients treated with atorvastatin 10 mg + ezetimibe 10 mg (EZ/Atorva) vs. increasing the atorvastatin dose to 40 mg. METHODS Patients ≥ 65 years with at...

BACKGROUND Behçet's disease (BD)-associated uveitis causes retinal damage leading to severe visual disturbance. The early morphological changes in the retina are revealed by disappearance or disruption of the external limiting membrane (ELM), inner segment ellipsoid zone (EZ) and cone interdigitation zone (CIZ) in the outer retina shown on spectral domain-optical coherence tomography (SD-OCT). ...

Unilateral ureteral obstruction of rabbit kidney results, after 3 days, in an exaggerated release of prostaglandin E2 and thromboxane Az by the ex vivo perfused hydronephrotic kidney (HNK) but not by the surgically unaltered contralateral kidney (CLK). Both cyclooxygenase (PG endoperoxide synthetase) and thromboxane synthetase activities increased 20-40fold in cortical microsomes prepared from...

FilterWire EZ（FW-EZ）でのcarotid artery stenting（CAS）においてflow impairmentを起こす要因は明確ではない．本研究ではFW-EZにおけるflow impairmentを起こす要因について後方視的に評価を行い，FW-EZでのCASの治療適応について再検討した．

The zoonotic Mycobacterium bovis is a pathogen of significance in the dairy industry in many parts of the world. Although the pathogen primarily affects cattle, it has a wide host range including humans. A cross-sectional study was carried out in three agro-ecological zones of Tanzania, namely the southern highlands zone (SHZ), eastern zone (EZ) and northern zone (NZ), to examine the status of ...

Abstract: In a rural community comprising 35000 population, 510 infants born within a ten-month period were enrolled from a birth cohort. They were allocated into three equal groups of 170 Two types of measles vaccin es, namely medium titre (4.7 log pfu/ml) Edmonston­ Zagreb(EZ) or an equivalent dose of Connaught(CON) vaccine were used in a double blind randomized trial to compare their immunol...

PURPOSE To determine the value of topographic spectral-domain optical coherence tomography (SD-OCT) imaging features assessed after macular hole repair surgery in predicting visual acuity (VA) outcomes. METHODS An automated algorithm was developed to topographically outline and quantify area, extent, and location of defects in the ellipsoid zone (EZ) band and inner retina layers in SD-OCT sca...