Lycopene, beta-carotene, coenzyme Q10, and lutein are minor constituents of palm oil that removed during biodiesel production to produce light-coloured oils. With the aim investigate recovery these valuable compounds, a separation method was developed quantify carotenoids Q10 in by ultra-high-performance supercritical fluid chromatography. Due presence interferents, different clean-up procedure...

AIM This study tests the hypothesis that statins (HMGCoA reductase inhibitors) inhibit carcinogenesis and that this effect may be mediated by the statin-induced inhibition of ubiquinone synthesis. MATERIALS AND METHODS The effects of lovastatin, with and without addition of ubiquinone, were studied in a rat model for chemically induced hepatocarcinogenesis. Intermediates in the mevalonate pat...

BACKGROUND Selenium and coenzyme Q10 is essential for important cellular functions. A low selenium intake is reported from many European countries, and the endogenous coenzyme Q10 production is decreasing in the body with increasing age. Supplementation with selenium and coenzyme Q10 in elderly have shown reduced cardiovascular mortality and reduced levels of markers of inflammation. However, m...

Honey bee queen quality is a critical factor of colony performance. Indications such qualities can manifest themselves through morphological traits as wet weight and thorax width. Improving characteristics driven in part by nutritional provision queen-cell-builder hives. We investigated the potential to improve adding coenzyme Q10 (endogenous antioxidant) caffeine (central nervous system stimul...

Coenzyme Q is a lipid that participates to important physiological functions. Coenzyme Q is synthesized in multiple steps from the precursor 4-hydroxybenzoic acid. Mutations in enzymes that participate to coenzyme Q biosynthesis result in primary coenzyme Q deficiency, a type of mitochondrial disease. Coenzyme Q10 supplementation of patients is the classical treatment but it shows limited effic...

OBJECTIVE To assess the effects of Coenzyme Q10 supplementation on glycaemic control, oxidative stress and adiponectin levels in people with type 2 diabetes. METHODS The randomised, single-blind, placebo-controlled study was conducted in the city of Shiraz, Iran, in 2012 and comprised type 2 diabetes subjects recruited from various health facilities. Subjects and controls received 100mg Coenz...

In a multicentric, open, preliminary trial, we evaluated the use of ginkgolide B, a herbal constituent extract from Ginkgo biloba tree leaves, in the prophylactic treatment of migraine with aura (MA). Fifty women suffering from migraine with typical aura, or migraine aura without headache, diagnosed according to International Headache Society criteria, entered a six-month study. They underwent ...

conclusions the weakness of the literature with regard to coenzyme q10 is about its effects in patients with severely diminished sperm densities and the physiologic steps of morphologic improvements. results the increase in mean values of concentration after the ubiquinol treatment was not statistically significant (p value = 0.065). however, the changes in morphology and motility (fast progres...

Ischemia/Reperfusion (I/R)-induced cerebral injury has been reported as a leading cause of deathand long-term disabilities. Hippocampus is an area which is more sensitive to be affected by I/Rand hypoxic conditions. Coenzyme Q10 is a strong antioxidant which plays a role in membranestabilization. This study aims to investigate the possible role of CoQ10 in ameliorating thehistomorphological cha...