Background: Based on the reports, Aloe vera extract, a herbal medicine, has antimicrobial and anti-inflammatory effects. Also, this medicinal plant has considerable effects on innate immunity through cytokine secretion which resist fungal infections such as Candida albicans. Moreover, Aloe vera is considered as immunomodulatory agent and regulate inflammatory responses. Materials and Methods: I...

Objectives: This study aimed to evaluate the effect of a testosterone enanthate anabolic steroid on gene expression inflammatory factors in kidney tissue female rats following eight weeks resistance training. Methods: Twenty-one Wistar weighing 200 ± 20 g, aged weeks, were prepared from Iran Pasture Institute. Following week for acclimatization, randomly divided into three groups: control (n = ...

We present a label-free biosensor based on electrochemical impedance spectroscopy for the detection of proinflammatory cytokine Tumor Necrosis Factor (TNF-α). Secretion of TNF-α has been correlated to the onset of various diseases including rheumatoid arthritis, Crohn’s disease etc. Gold electrodes were patterned on a silicon substrate and self assembled monolayer of dithiobis-succinimidyl prop...

background: because of its effect on speech and swallowing, laryngeal squamous cell carcinoma is a devastating disease which has been shown to have a poor survival rate. abundant research is being carried out in search of novel biomarkers that can aid the process of diagnosis and treatment of this disease. fxyd3, a modulator of na/k-atpase, is presented as a biomarker in some cancers. fxyd3 exp...

background inflammatory bowel disease (ibd) is a chronic, relapsing, inflammatory disorder of the gastrointestinal tract that includes two entities, crohn`s disease (cd) and ulcerative colitis (uc). as with other complex diseases, both genetic susceptibility and environmental factors play role in the pathogenesis of these diseases. the tumor necrosis factor α (tnf-α) gene is located in the ibd3...

By using LNCaP and its derivative cell lines, we first observed an association between tumor necrosis factor-alpha (TNF-alpha) resistance and hormone independence. Moreover, we found that the expression of tumor necrosis factor receptor-associated death domain (TRADD) was reduced in androgen deprivation-independent cells compared with that in androgen deprivation-dependent cells. TRADD is a cru...

Abstract Background: Breast cancer is the most common in women. The occurrence of metastasis breast should be detected early. Tumor necrosis factor-α (TNF-α) involved every step carcinogenesis process. A rise TNF-α level linked to advancement cancer. We aimed determine association between levels and metastases. Methods: An analytic cross-sectional study was conducted on women with treated at On...

conclusions in the chinese han population that we studied, nafld patients who carry the tnf-α-238 ga polymorphism have an increased risk of developing cad. mechanisms underlying this potentially important association require further investigation. background cardiovascular events account for the main cause of death in patients with non-alcoholic fatty liver disease (nafld), and are largely infl...