Virtually every neurosurgeon wishes for a new and better method, preferably noninvasive, to rapidly and accurately see residual malignancy during surgery to remove a tumor. A new study by researchers in the Department of Biomedical Engineering at Stony Brook University in Stony Brook, N.Y., might someday grant this wish. Researchers combined a new brain tumor–targeting contrast agent that diffe...

Glioma is one of the most challenging types of brain tumors to treat or control locally. One of the main problems is to determine which areas of the apparently normal brain contain glioma cells, as gliomas are known to infiltrate several centimeters beyond the clinically apparent lesion that is visualized on standard Computed Tomography scans (CT) or Magnetic Resonance Images (MRIs). To ensure ...

The purpose of this investigation was to analyze the correlation between CT size and gross pathologic size for subjects with primary hepatocellular carcinoma (HCC). This analysis included 174 patients with HCC who underwent surgery. Enhanced computed tomography (CT) was performed up to 30 days before surgery. After resection, the size of the tumor on gross pathologic examination was recorded. T...

This is a case report on stereotaxic (Stereotactic Body Radiotherapy-SBRT) for lung cancer located in the left lower lobe (Segment 6, S6). There have been no reports on marked displacement of the peripheral lung cancer during radiotherapy. A pulmonary nodule was discovered on computed tomography (CT) conducted for a persistent cough in an 87-year-old male. According to diagnostic imaging, this ...

The completeness of tumor removal during surgery is dependent on the surgeon's ability to differentiate tumor from normal tissue using subjective criteria that are not easily quantifiable. A way to objectively assess tumor margins during surgery in patients would be of great value. We have developed a method to visualize tumors during surgery using activatable cell-penetrating peptides (ACPPs),...

BACKGROUND To review the outcome of using radiofrequency ablation (RFA) for patients with close resection margin during hepatectomy. METHODS From Oct 2004 to Sept 2013, 862 patients received hepatectomy for hepatocellular carcinoma (HCC) in the Department of Surgery, Queen Mary Hospital in Hong Kong. Fourteen patients received additional RFA because of close resection margin (<1 cm) during th...

OBJECTIVES/HYPOTHESIS Evaluate effectiveness of resection of oral cavity cancer with a standardized approach for margin evaluation. Primary end points were local control and survival. STUDY DESIGN Retrospective, nonrandomized, single institution. METHODS One hundred eight patients who underwent surgery for oral cancer were evaluated using specific anatomical pathology criteria. Frozen secti...

Introduction: To increase breast MRI specificity, [1,2] better assessment of lesion morphology is needed. This is especially true for differential diagnosis of fibro-adenomas, which present with DCE curves similar to those of malignant lesions. Furthermore, the smaller the lesion, the more difficult it is to assess its morphology. Yet, it is these small lesions where high specificity is paramou...

Rotational radiotherapy treatments such as volumetric modulated arc therapy (VMAT) can have superior overall quality while having shorter delivery time with respect to conventional intensity modulated radiotherapy (IMRT). As with conventional treatments, intrafractional tumor motion is a major source of uncertainty in dose application. To ensure full tumor coverage the planning target volume (P...