نتایج جستجو برای: tumor growth factor

تعداد نتایج: 1743425  

Journal: :گوارش 0
mehdi seilaniantoosi houshang rafatpanah jalil tavakkolafshar mohammadreza ghavamnassiri hamidreza sima mona malekzadehmoghani

background host genetic and environmental factors are involved in development of gastric cancer. tumor necrosis factor (tnf)-î±| has a key role in helicobacter pylori -induced gastritis. we analyzed the association between tnf-î± polymorphism and the risk of gastric cancer in an iranian population residing in northeastern iran. materials and methods in a case-control study, the genotyping was c...

Journal: :iranian red crescent medical journal 0
tao zhang department of gastrointestinal surgery, the center hospital of wuhan, wuhan, china; department of gastrointestinal surgery, the center hospital of wuhan, wuhan, china. tel/fax: +86-2782211448 hui wang department of gastrointestinal surgery, the center hospital of wuhan, wuhan, china liang han department of gastrointestinal surgery, the center hospital of wuhan, wuhan, china

conclusions traf6 plays an important role in the onset of colon cancer; therefore, drugs targeting it may have great clinical significance in the treatment of this disease. results the positive expression rate of traf6 in tumor tissues was 66.7%, which was significantly higher than in normal paracancerous tissues (18.5%). the positive expression rate of traf6 was significantly correlated with d...

Journal: :Cancer research 2005
W Gregory Roberts Pamela M Whalen Erik Soderstrom Garrett Moraski Joseph P Lyssikatos Huifen-F Wang Beth Cooper Deborah A Baker Douglas Savage Deepak Dalvie James A Atherton Sherry Ralston Ruby Szewc John C Kath Jing Lin Cathy Soderstrom George Tkalcevic Bruce D Cohen Vince Pollack Wayne Barth Will Hungerford Ethan Ung

CP-673,451 is a potent inhibitor of platelet-derived growth factor beta-receptor (PDGFR-beta) kinase- and PDGF-BB-stimulated autophosphorylation of PDGFR-beta in cells (IC(50) = 1 nmol/L) being more than 450-fold selective for PDGFR-beta versus other angiogenic receptors (e.g., vascular endothelial growth factor receptor 2, TIE-2, and fibroblast growth factor receptor 2). Multiple models have b...

Journal: :Bioorganic & Medicinal Chemistry Letters 2010

Journal: :Journal of Cancer Research and Therapeutics 2018

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