Aim: To obtain clinicopathological characteristics of colorectal cancer among young native Indonesians and to assess MLH1, MSH2, and SMAD4 protein expressions, comparing them with a matched population of colorectal cancer patients aged 60 years old and older. Methods: Medical records of colorectal cancer patients aged 40 years or younger and 60 years or older from several hospitals in three Ind...

PURPOSE Our purpose was to evaluate cerebral glioma grade by using normal side creatine (Cr) as an internal reference in multi-voxel 1H-MR spectroscopy. MATERIALS AND METHODS We examined 25 adult patients with glial brain tumors. Ratios of maximum Cho/Cr (normal) (max- Cho/Cr(n)) and minimum NAA/Cr(normal) (min-NAA/ Cr(n)) were determined using Cr levels in the normal parenchyma. In addition, m...

Renal cell carcinoma (RCC) is the most common malignancy of the adult kidney. A variety of proteins have been investigated for their use as prognostic tumor markers. At present, there are conflicting reports concerning HER2 expression in RCC. PURPOSE: The aim of this study is to evaluate the expression of HER2 protein in patients with renal cell carcinoma (RCC) and to determine the relationship...

  Abstract   Background: Squamous cell carcinoma (SCC) constitutes the main oral malignancy .   Parallel to better understanding of molecular and genetic patterns of tumor behavior, more precise correlation of tumor markers such as Epidermal Growth Factor (EGF) and Laminin-5 are sought to estimate macroscopic and microscopic tumor status .   Methods: We conducted a cross-sectional study collect...

An 18-year-old female black leopard (Panthera pardus) showed renal failure, leukocytosis and presence of subcutaneous masses in the lower abdominal region and right shoulder; she eventually died. Histopathological observations included a mammary gland carcinoma with comedo, solid and tubulopapillary patterns in subcutaneous tissue, and highly proliferated tumor cells in systemic organs. The tum...

Introduction In clinical monitoring of brain tumors, Perfusion Weighted Imaging (PWI) contributes to tumor grading and to assess the response to treatment [1]. Beyond tumor perfusion, tumor hypoxia determines the response of various therapeutic approaches including radiotherapy. All these parameters may be mapped with MRI. However, the integration of several MRI maps is difficult. This wealth o...

Although it has been recognized for many centuries that neoplastic tissue is more vascular than its normal counterpart, it is only since Folkmans' hypothesis on antiangiogenesis (1) that a more quantitative method for measuring angiogenesis in tissue sections has been pursued. Folkman and colleagues recognized that quantitation of the tumor vasculature might play an important a role in predicti...

BACKGROUND This study was performed to assess the 2006 introduced ENETS TNM-classification with respect to patient survival and surgical approach for patients who underwent surgery for a neuroendocrine tumor of the pancreas (PNET). METHODS Between 2001 and 2010 38 patients after resection of a PNET were investigated regarding tumor localization and size. Further, patient survival with regards...