UNLABELLED Learning disorders are often magnified by auditory processing disorders (APD). OBJECTIVE This paper aims to verify whether individuals with reading and writing disorders and P300 latencies above the average also present altered Staggered Spondaic Word (SSW) and speech-in-noise test results suggestive of APD. MATERIALS AND METHODS This is a cross-sectional cohort study. Twenty-one...

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Catechol-O-methyltransferase (COMT; E.C. 2.1.1.6) is a ubiquitous enzyme in nature that plays an important role in the metabolism of catechol neurotransmitters and xenobiotics. In particular, inactivation of drugs such as L-3,4-dihydroxyphenylalanine (L-DOPA) via O-methylation is of relevant pharmacological importance, because L-DOPA is currently the most effective drug used in the treatment of...

Significance of microRNAs (miRs), small non-coding molecules, has been implicated in a variety of biological processes. Here, we recruited retroviral insertional mutagenesis to obtain induction of an arbitrary noncoding RNAs, and coupled it with a cell based loss-of-function (5-Aza-2'-deoxycytidine (5Aza-dC)-induced senescence bypass) screening system. Cells that escaped 5-Aza-dC-induced senesc...

Mutations in the thymidine kinase (TK) gene of herpes simplex virus (HSV) have been associated with resistance to acyclovir (ACY) and possible recognition of neurotropic strains. We sequenced a 335-bp segment of the TK gene to determine the frequency of mutations in HSV strains recovered from dermal, genital, and cerebrospinal fluid (CSF) specimens (n = 200; 102 HSV type 1 [HSV-1] 98 HSV-2 stra...

while true do (noncritB; flagB := true; turn := A; waitfor (flagA = false) ∨ (turn = B); critB ; flagB := false) . A global state of our system S = A‖B (processes A,B running in parallel; they communicate by shared variables) can be described by the values of a few (boolean) variables, i.e., by a (column) vector from {0, 1} for some fixed k. Our system S thus determines (can be equated with) a ...

One of the major drawbacks of the symmetric QR algorithm is that it is not parallelizable. Each orthogonal similarity transformation that is needed to reduce the original matrix A to diagonal form is dependent upon the previous one. In view of the evolution of parallel architectures, it is therefore worthwhile to consider whether there are alternative approaches to reducing an n × n symmetric m...

The structural and electronic properties of gold decorated Si(335) surface are studied by means of density-functional calculations. The resulting structural model indicates that the Au atoms substitute some of the Si atoms in the middle of the terrace in the surface layer. Calculated electronic band structure near the Fermi energy features two metallic bands, one coming from the step edge Si at...

We report on a 151-ks net exposure Suzaku observation of the narrow-line Seyfert 1 galaxy Mrk 335. The 0.5–40 keV spectrum contains a broad Fe line, a strong soft excess below about 2 keV and a Compton hump around 20–30 keV. We find that a model consisting of a power law and two reflectors provides the best fit to the time-averaged spectrum. In this model, an ionized, heavily blurred, inner ref...