Reactive oxygen species (ROS) have been reported to be critical cellular mediators of experimental ischemic acute renal failure (ARF). This conclusion is based on observations that in the renal artery occlusion (RAO) model of ARF, antioxidant drugs confer protection and that renal malondialdehyde (MDA) concentrations, an index of lipid peroxidation, rise in the postischemic period. Human ischem...

BACKGROUND Cardiorenal syndrome is now frequently recognized, and the combined dysfunction of heart and kidney increases morbidity and mortality. This study aimed to investigate possible mechanisms that underlie renal damage following heart dysfunction using a rat myocardial infarction model, focusing on the inflammatory pathway. METHODS Rats were randomized into four groups: normal, volume d...

Using the isolated rat kidney perfused with an artificial medium containing glucose as the sole fuel, we studied the renal handling of immunoreactive arginine vasopressin (AVP) and determined the effect of various factors on the ability of the kidney to remove AVP. In control kidneys perfused with AVP at concentrations below 116 muU/ml, the organ clearance of AVP (OC(AVP)) was 1,145+/-47 (SE) m...

BACKGROUND After insult to the kidney, a renal fibrotic process is initiated with sustained inflammation, fibroblast activation and accumulation of extracellular matrix (ECM). Tamoxifen has been used as an anti-estrogen for the prevention and treatment of breast cancer. In this study, we investigated the protective effects of tamoxifen on unilateral ureteral obstruction (UUO)-induced renal tubu...

Tubal ligation is a surgical procedure for sterilization in which a woman's fallopian tubes are clamped and blocked, or severed and sealed, either method of which prevents eggs from reaching the uterus for implantation. However, fertilization can still occur in the fallopian tubes. While its benefits, such as effectiveness in protecting against pregnancies, minimal need for long-term follow-up ...

Tubal ligation is a surgical procedure for sterilization in which a woman's fallopian tubes are clamped and blocked, or severed and sealed, either method of which prevents eggs from reaching the uterus for implantation. However, fertilization can still occur in the fallopian tubes. While its benefits, such as effectiveness in protecting against pregnancies, minimal need for long-term follow-up ...

Heme oxygenase-1 (HO-1), a cytoprotective gene, is commonly induced in renal tubules in the diseased kidney. Because proteinuria is a hallmark for kidney disease, we examined the relationship between proteinuria and tubular induction of HO-1, specifically questioning whether increased trafficking of protein across the renal tubular epithelium, as a consequence of proteinuria, induces tubular ex...

superior mesenteric artery (sma) aneurysm is a rare disease. in this case report, we present a 32 years old woman who was admitted to our hospital with chronic abdominal pain. sma aneurysm was diagnosed after radiological evaluation. the patient underwent ligation of the superior mesenteric artery aneurysm and remained well 12 months after the surgery.

introduction: regret after sterilization, not only requires an expensive surgical procedure for recanalization, but also can affect the couples’ inter and intra-relationships. whence, undergoing sterilization in sistan and baluchestan has the lowest rate compared to other provinces, the habitants’ regret after sterilization may further discourage other volunteers of the procedures. therefore, t...