BACKGROUND AND OBJECTIVE The diagnosis of tuberculous pleurisy by analysis of pleural fluid using standard diagnostic tools is difficult. Recently, T-cell interferon-γ release assays (IGRA) have been introduced for the diagnosis of tuberculous pleurisy. The aim of the present meta-analysis was to establish the overall diagnostic accuracy of IGRA on both pleural fluid and peripheral blood, for d...

PURPOSE Tuberculous pleurisy is the most frequent extrapulmonary manifestation of tuberculosis. In spite of adequate treatment, pleural fibrosis is a common complication, but the mechanism has not been elucidated. This study is to determine whether epithelial to mesenchymal transition (EMT) of mesothelial cells occurs in tuberculous pleurisy. MATERIALS AND METHODS Normal pleural mesothelial c...

1 Valdes L, Sanjose E, Alvarez D, Sarandeses A, Pose A, Chomon B, et al. Diagnosis of tuberculous pleurisy using the biologic parameters adenosine deaminase, lysozyme, and interferon gamma. Chest 1993; 103:458-65 2 Piras MA, Gakis C, Budroni M, Andreoni C. Adenosine deaminase activity in pleural effusions: an aid to differential diagnosis. Br Med J 1978; ii:1751-52 3 Van Keimpema AR, Slaats EH,...

Background: There are no available reference values on treatment of tuberculous pericarditis in the literature and seems it remains controversial. Methods: Twenty nine patients (age ranges 9 75 years) with tuberculous pericarditis were studied retrospectively in this study. Medical recording of all patients undergoing operation for pericardial tuberculosis at the Cardiothoracic ward of Tabriz U...

The World Health Organization currently estimates that nearly two billion people, or one-third of the world's population, are infected by tuberculosis, and that roughly 10% of the infected people are symptomatic. Tuberculosis affects the lungs in 80% of patients, while in the remaining 20% the disease may affect other organs, including the eye. Uveitis can be seen concurrently with tuberculosis...

BACKGROUND Diagnosis of tuberculous serositis remains a challenge. The aim of this study was to evaluate the diagnostic efficiency of T-SPOT.TB on serous effusion mononuclear cells (SEMC) for diagnosing tuberculous serositis in a high TB burden area. METHODS The present prospective study enrolled patients with suspected tuberculous serositis in a tertiary referral hospital in Beijing, China, ...

INTRODUCTION Tuberculous otitis is a diagnostic problem due to the difficulty to obtain microbiological, histomorphological and cytological confirmation of the disease. OBJECTIVE Our objective was to compare clinical and radiological characteristic and development of otogenic complications in patients with tuberculous otitis and otitis with cholesteatoma as the most destructive form of chroni...

BACKGROUND Tuberculous epididymitis is one of the causes of chronic epididymal lesions. It is difficult to diagnose in the absence of renal involvement. AIM To profile isolated tuberculous epididymitis and to assess our approach in the evaluation of this group of patients. SETTING AND DESIGN Retrospective study done at Christian Medical College, Vellore, South India. METHODS AND MATERIALS...

Metastatic tuberculous abscesses or cutaneous tuberculous gummas occur mostly by reactivation of ancient cutaneous foci and is triggered mainly by pharmacological immunosuppression, diabetes mellitus, alcoholism or acquired immunodeficiency syndrome. The present case report refers to a 33-year-old male patient with polymyositis and a previous diagnosis of treated pulmonary tuberculosis. He pres...

The author presents a young patient presenting with lower gastrointestinal hemorrhage due to tuberculous appendicitis. Though an ileo-cecal region is the most frequent site of involvement of the intestinal tuberculosis, vermiform appendix involvement is rare. Moreover, intestinal tuberculosis is an uncommon cause of lower gastrointestinal hemorrhage. Therefore, bleeding from tuberculous appendi...