The sensitive and tightly regulated feedback control system, thyroid gland autoregulation, and the large intrathyroidal and extrathyroidal storage pools of thyroid hormone serve to provide a constant supply of thyroid hormone to peripheral tissues in the face of perturbations imposed by the external environment, chemicals and drugs, and a variety of diseases processes. The thyroid is subject to...

The main focus of this study is to apply a computational tool for the flow analysis of the turbine engine that has been tested with ice crystal ingestion in the Propulsion Systems Laboratory (PSL) at NASA Glenn Research Center. The PSL has been used to test a highly instrumented Honeywell ALF502R-5A (LF11) turbofan engine at simulated altitude operating conditions. Test data analysis with an en...

‘Gestational hyperthyroidism’ is a clinical condition characterized by thyrotoxicosis and hyperemesis gravidarum and generally occurs in 1–2% of all normal pregnancies. It represents an extreme degree of morning nausea and vomiting in early pregnancy, accompanied by weight loss, ketonemia, acetonuria, and profound volume depletion. Within the last decade, the association of abnormal thyroid fun...

Vitamin A (VA) deficiency (VAD) and the iodine deficiency disorders (IDD) affect > 30% of the global population and these deficiencies often coexist in vulnerable groups. VAD has multiple effects on the pituitary-thyroid axis; VA status modulates thyroid gland metabolism, peripheral metabolism of thyroid hormone, and production of thyrotropin (TSH) by the pituitary. Findings from Africa childre...

•Environmental- and dietary-driven seasonality in laboratory test data is well known•Population-wide Danish lab were related to mortality, sex, age trends•A seasonal reference interval modification method proposed•Seasonal improved association rates with diagnoses In health care, tests are used help determine a diagnosis follow patients over time. Test results typically calculated from sampled ...

The Texas Towers were a series of platforms installed off the U.S. East coast in the 1950’s to support early warning radar facilities. Texas Tower No. 4 (TT4) was installed in a water depth of 185 feet in 1957. At this time, TT4 was heralded as an ‘engineering marvel’, a major innovative ocean engineering accomplishment. However, problems in the structural integrity of the platform developed af...

In previous papers we have described the basic elements for building an economic model consisting of a group of artificial traders functioning and adapting in an environment containing real stock market information. We have analysed the feasibility of the proposed approach by comparing the final wealth generated by such agents over a period of time, against the wealth of a number of well known ...

Examining traditional and contemporary professional development practices of youth-serving organizations can inform practices across Extension, particularly in light of the barriers that have been noted for effectively developing the professional competencies of Extension educators. With professional development systems changing quickly, particularly through online education and blended learnin...