Minor degrees of congenital malformation of the heart are fairly commonly discovered at Toutine post-mortem examinations and are compatible with normal life and age. Major degrees of congenital malformations are rarer and usually incompatible with long life. However, some who have lived to a good age are recorded. The earliest imperfect descriptions of bilocular hearts are by Pozzi in 1673 and ...

OBJECTIVES The purpose of this study was to identify trends and factors associated with outcomes of persistent truncus arteriosus (PTA). BACKGROUND Although there have been significant improvements, PTA continues to be associated with significant morbidity and mortality. METHODS We undertook a review of all consecutive cases of PTA (n = 205) presenting at our institution from 1953 to 1997. ...

Congenital thoracic arterial anomalies can be incidentally detected in adults from imaging studies performed for other indications. Multidetector computed tomography plays a critical role in the noninvasive assessment of these anomalies and associated cardiac, mediastinal, or parencyhmal changes by providing volumetric data. Radiologists should be familiar with imaging findings ...

To investigate the contribution of cranial neural crest cells to the developing cardiovascular system in the chick embryo, cauterization of various regions of cranial neural crest was performed. Five regions may be distinguished, each of which contributes mesenchyme to pharyngeal (branchial) arches 1 through 4 and 6. Ablation of arch 3, 4, and 6 regions resulted in a high incidence of persisten...