Gandin and Murphy have shown that if a skill score is linear in the scoring matrix, and if the scoring matrix is symmetric, then in the 2-event case there exists a unique, \equitable" skill score, namely the True Skill Score (or Kuipers' performance index). As such, this measure is treated as preferable to other measures because of its equitability. However, in most practical situations the sco...

True umbilical cord knot appears to be a relatively common complication that occurs in 0.3%-1.3% of all pregnancies and it is correlated with an increased incidence of SGA infants, premature birth, need for neonatal intensive care and fetal death. The aim of the article was to evaluate the incidence of the true umbilical cord knot in the University Emergency Hospital, Bucharest, for a period of...

In this thesis, we address the identification of biomarkers in high-dimensional omics data. The identification of valid biomarkers is especially relevant for personalized medicine that depends on accurate prediction rules. Moreover, biomarkers elucidate the provenance of disease, or molecular changes related to disease. From a statistical point of view the identification of biomarkers is best c...