Adenoviruses are nonenveloped doublestranded DNA viruses that were fi rst isolated from adenoidal cells in 1953 as part of a project searching for the virus causing the common cold. There are currently 57 recognized serotypes of human adenovirus, which can be divided into the subgroups (or species) A to G. There is tropism among these subgroups, with subgroups A and F typically causing infectio...

Parvovirus B19 has an extreme tropism for human erythroid progenitors. Here we propose the hypothesis explaining the tropism of human parvovirus B19. Our speculations are based on experimental results related to the capsid proteins VP1 and VP2. These proteins were not detectable in nonpermissive cells in course of these experiments, although the corresponding mRNAs were synthesized. Our interpr...

Arthropod-borne viruses (arboviruses) are a significant cause of human and animal disease worldwide. Multiple interactions between virus and the host innate immune system ultimately determine the pathogenesis and clinical outcome of the infection. Evidence is rapidly emerging that suggests viral glycans play a key role in viral pathogenesis by regulating host cell tropism and interactions with ...

Widespread occurrence of H9N2 low pathogenic avian influenza (LPAI) viruses in many Asian countriesduring the past decade has resulted in the need for evaluation of the pathogenesis of H9N2 virus infection. In this study, tissue tropism and dissemination of A/Chicken/Iran/772/1998(H9N2) virus throughout the body of broiler chickens were investigated. The clinical signs, gross lesions and antibo...

Typical stereotropic orientation toward a lateral surface of contact is obtained in young rats and mice, and with adult mice congenitally blind. Removal of vibrissae or tail or both does not essentially affect this response. Equal contact on both sides of the body prevents orientation toward either source of contact. Unequal contact areas on the two sides leads to orientation toward the more ex...