Pendahuluan: Pinang muda (Areca Catechu) dan asam kandis (Garcinia Xanthochymus) merupakan salah satu tanaman yang banyak digunakan dalam pengobatan tradisional. Kandungan fenol, flavonoid, tanin, saponin, triterpenoid, alkaloid, xanton, steroid/triterpenoid glikosida sangat baik untuk menghambat pertumbuhan bakteri, anti oksidan, imflamasi sehingga bagus mempercepatan penyembuhan luka perineum...

A new dammarane-type triterpene saponin was isolated from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino. Its structural elucidation was accomplished mainly on the basis of the interpretation of spectroscopic data, such as IR, HR-TOF-MS and NMR. Its cytotoxic activity was evaluated against one human cancer cell line HL-60 using MTT assay.

Two new triterpenoid saponins (1, 2) were isolated from the roots of Gypsophila altissima L. (Caryophyllaceae), together with a known compound (3). The structures of new saponins were established as quillaic acid 3-O-beta-D-xylopyranosyl-(1-->3)-beta-D-glucuronopyranoside (1), and 3-O-beta-D-galactopyranosyl-(1-->2)-[beta-D-xylopyranosyl-(1-->3)]-beta-D-glucuronopyranosyl quillaic acid 28-O-(6-...

Two minor triterpenoid saponins, ardisicrenoside G [3 beta-O-{alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl-(1-->4)- [beta-D-glucopyranosyl-(1-->2)]-alpha-L-arabinopyranosyl}-16 alpha,28-dihydroxyolean-12-en-30-oic acid] and ardisicrenoside H [3 beta-O-{beta-D-xylopyranosyl-(1-->2)-beta-D- glucopyranosyl-(1-->4)-[beta-D-glucopyranosyl-(1-->2)]-alpha-L- arabinopyranosyl}-16 alpha,28-dihy...

Five new triterpenoid saponins, heinsiagenin A 3-O-[α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl-(1→2)]-β-d-glucopyranoside (1), heinsiagenin A 3-O-[α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl-(1→2)]-[β-d-glucopyranosyl-(1→4)]-β-d-glucopyranoside (2), 2α-hydroxyheinsiagenin A 3-O-[α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranosyl-(1→2)]-β-d-glucopyranoside (3), 2α-hydroxyheinsiagenin A 3-O-[β-d-glu...

Ginkgo biloba L. has attracted much attention due to its medicinal properties, particularly those of terpenoid and flavonoid contents. However, the content utilization efficiency terpenoids remain low. The enzyme 3-hydroxy-3-methylglutaryl CoA synthase (HMGS) is a major rate-limiting factor, RNA-seq revealed that mRNA expression this differentially expressed during biosynthesis. Here, we invest...

We and other studies have elucidated single molecules that can attenuate aging and extend longevity. Indeed, these molecules could prevent age-associated diseases simultaneously and probably extending healthy-life spans. In this review, we discuss recent advances, controversies, opportunities and challenges surrounding ursolic acid (UA) in relationship with aging. In this regard, UA also known ...