This report has not been formally peer reviewed. The opinions expressed here reflect those of the authors, and not necessarily those of their home institutions or supporting organizations. Abstract This analytical report is the outcome of a restudy that was undertaken in January 2005 of an original study undertaken in 1993 of the impact of HIV/AIDS on agricultural production systems and livelih...

17β-hydroxyestra-4,9,11-trien-3-one (Trenbolone) Exhibits Tissue Selective Anabolic 1 Activity: Effects on Muscle, Bone, Adiposity, Hemoglobin, and Prostate 2 3 Joshua F. Yarrow, Christine F. Conover, Sean C. McCoy, Judyta A. Lipinska, Cesar A. 4 Santillana, John M. Hance, Darryl F. Cannady, Tisha D. VanPelt, Joshua Sanchez, Bryan P. 5 Conrad, Jennifer E. Pingel, Thomas J. Wronski, and Stephen ...

Red cell aplasia developed in a case of Wilson's disease following an increase in D-penicillamine dosage after 14 years' treatment. In vitro study of the effect of D-penicillamine on 59Fe incorporation by marrow cells did not suggest that the patient's erythropoiesis was particularly sensitive to D-penicillamine or determine the mechanism of drug toxicity. However, three weeks after the drug wa...

This study determined the mechanisms and patterns of antimicrobial resistance among the isolates obtained from different wards of a teaching hospital in the city of Mashhad in north-east Iran. Between January 2012 and the end of June 2012, 36 isolates of Acinetobacter baumannii were collected from different wards of Ghaem Hospital. Antimicrobial susceptibility testing and epsilometer testing (E...

Two probes consisting of vitamin B(12) (CNCbl) conjugated to Gd chelates by esterification of the ribose 5'-OH moiety, Gd-DTPA-CNCbl (1; DTPA = diethylenetriamine-N,N,N',N'',N''-pentaacetic acid) and Gd-TTHA-CNCbl (2; TTHA = triethylenetetramine-N,N,N',N'',N''',N'''-hexaacetic acid), have been synthesised and characterised. The crystal structure of a dimeric form of 1, obtained by crystallisati...

(2014) Preparation of graphene oxide/epoxy nanocomposites with significantly improved mechanical properties. Notice: Changes introduced as a result of publishing processes such as copy-editing and formatting may not be reflected in this document. For a definitive version of this work, please refer to the published source: The effect of graphene oxide (GO) on the mechanical properties and the cu...

BACKGROUND Antimicrobial agents have been widely used in animal farms to prevent and treat animal diseases and to promote growth. Antimicrobial agents may change the bacterial community and enhance the resistome in animal feces. We used metagenome-wide analysis to investigate the changes in bacterial community, variations in antibiotic resistance genes (ARGs), and their bacterial hosts in the f...

We have utilized processing-defective derivatives of the outer membrane maltoporin, LamB, to study protein trafficking functions in the cell envelope of Escherichia coli. Our model proteins contain amino acid substitutions in the consensus site for cleavage by signal peptidase. As a result, the signal sequence is cleaved with reduced efficiency, effectively tethering the precursor protein to th...

Acinetobacter baumannii is one of the most antibiotic-resistant pathogens in clinical medicine, and extensively drug-resistant (XDR) strains are commonly isolated from infected patients. Such XDR strains are already resistant to traditional selectable genetic markers, limiting the ability to conduct pathogenesis research by genetic disruption. Optimization of selectable markers is therefore cri...

The secondary amines found in b-PIBSI dispersants prepared by attaching two polyisobutylene chains to a polyamine core via two succinimide moieties were reacted with ethylene carbonate (EC). The reaction generated urethane bonds on the polyamine core to yield the modified b-PIBSI dispersants (Mb-PIBSI). Five dispersants were prepared by reacting 2 molar equivalent (meq) of polyisobutylene termi...