background: trichomoniasis is an extremely common sexually transmitted infection (sti) world­wide and is associated with important public health problems, including amplification of hiv transmission. this disease is in forms of symptomatic and asymptomatic in women and may de­pend on host as well as parasite variables. most of the studies reported from females are based on examination of vagina...

background: as for human trichomoniasis the host-parasite relationship is very complex, and the broad ranges of clinical symptoms are unlikely be attributable to a single pathogenic mechanism. specific random amplified polymorphic dna (rapd) markers of 490 bp, 720 bp and 460 bp using the primers tv-5, opa-6 and opa-11, respectively, were reported. this was the first description of possible ge­n...

background: trichomonas vaginalis , the causative agent of trichomoniasis, is responsible for more than half of all sexually transmitted infections (stis). the present study aimed to deter­mine the frequency of t. vaginalis infection and its clinical manifestations in sympto­matic pregnant women in the area based on four different diagnostic methods. methods: a total of 162 pregnant women with ...

OBJECTIVES To identify psychosocial predictors of Trichomonas vaginalis infection among low income African-American adolescent females living in a high risk urban area of the United States. METHODS Baseline plus 6 and 12 month follow up data collected as part of an HIV prevention intervention trial were utilised. The baseline sample consisted of 522 African-American females, 14-18 years of ag...

Trichomonas vaginalis is a common sexually transmitted protozoan parasite. Although often considered simply a nuisance infection, T. vaginalis has been implicated in premature rupture of placental membranes and increases in the risk of acquiring human immunodeficiency virus. Metronidazole, a 5-nitroimidazole, is currently the drug of choice to treat T. vaginalis infection. Because some patients...

trichomoniasis is one of the most common urinary-genital tract disease. the causal agent of trichomoniasis is flagellate protozoan called trichomonas vaginalis. metronidazole and tinidazole are the drug of choice for treatment. carcinogenic and embryo-teratogenic effects of the mentioned drugs and resistance to metronidazole has been reported. according to cytotoxic effects of medicinal herbs i...

Human immunodeficiency virus (HIV) infection is a pandemic that affects all parts of the globe. Current treatments fail to cure disease and for this reason there is significant interest in producing a vaccine to prevent HIV transmission, but clinical trials have proved disappointing. For this reason it is important to consider alternative measures to control incidence and prevalence of the dise...

Trichomonas vaginalis commonly causes vaginitis and perhaps cervicitis in women and urethritis in men and women. Macrophages are important immune cells in response to T. vaginalis infection. In this study, we investigated whether human macrophages could be involved in inflammation induced by T. vaginalis. Human monocyte-derived macrophages (HMDM) were co-cultured with T. vaginalis. Live, opsoni...

Objectives: To identify psychosocial predictors of Trichomonas vaginalis infection among low income African-American adolescent females living in a high risk urban area of the United States. Methods: Baseline plus 6 and 12 month follow up data collected as part of an HIV prevention intervention trial were utilised. The baseline sample consisted of 522 African-American females, 14–18 years of ag...