background: in addition to the well-defined histological criteria for squamous cell carcinoma (scc) and basal cell carcinoma (bcc), immunohistochemical techniques can be used in difficult cases for their differentiation. as differential diagnosis between trichoepithelioma (te) and bcc is sometimes difficult for the clinician and the pathologist, cd10 may be a useful marker for definite diagnosi...

Panfolliculoma is a distinctive and unusual benign follicular neoplasm. It shows differentiation towards all components of the hair follicle, including the upper and the lower segments. We report two cases of this rare disease. The first patient presented with a painful nodule on the scalp and the second patient had an asymptomatic skin-colored nodule on his left eyebrow. Histopathologic examin...

BCC: basal cell carcinoma FEP: fibroepithelioma of Pinkus INTRODUCTION First described by Herman Pinkus in 1953 as a premalignant epithelial neoplasm from which a basal cell carcinoma (BCC) may arise, fibroepithelioma of Pinkus (FEP) is viewed by most as a subtype of BCC, although some view it as a subtype of trichoblastoma. FEP classically appears clinically as a solitary skin-colored papule, ...

© 2010 The Authors. doi: 10.2340/00015555-0793 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Sebaceous naevi (organoid naevi) are hamartomatous proliferations that usually appear at birth or early in life, and are most commonly located on the scalp and face (1). They often present as round or oval lesions, and occasionally distribute in a linear pattern (2). Frequen...

Nevus sebaceus (NS) is a common congenital birthmark, and various tumors have been reported to develop in NS. Basal cell carcinoma (BCC) seldom occurs in NS, and it is very important to be able to clinicopathologically distinguish BCC from trichoblastoma. Herein, we describe a case of BCC and trichoblastoma occurring simultaneously in the same NS, including the differential dermoscopic features...

In the past decade the molecular basis of many inherited syndromes has been unravelled. This article reviews the clinical and genetic aspects of inherited syndromes that are characterised by skin appendage neoplasms, including Cowden syndrome, Birt-Hogg-Dube syndrome, naevoid basal cell carcinoma syndrome, generalised basaloid follicular hamartoma syndrome, Bazex syndrome, Brooke-Spiegler syndr...