Nineteenth-century somatic theories of madness required specific types of treatment that focused on the body of the afflicted. This treatment stressed the primacy of caring for the body as a route to curing the mind. Treatment through environment would facilitate a transfer of the salubrious nature of a well-ordered place of treatment to the body and the mind of the lunatic. Therefore, the desi...

This paper studies a reliable facility location problem with facility protection that aims to hedge against random facility disruptions by both strategically protecting some facilities and using backup facilities for the demands. An Integer Programming model is proposed for this problem, in which the failure probabilities of facilities are site-specific. A solution approach combining Lagrangian...

— We treat a discrete uncapacitated facility location problem where the installation cost per facility is a gênerai nonlinear function of the number of established facilities. Assuming a convexity proper ty, Mirchandani and Jagannathan developed a heur is tic solution procedure for this problem. Hère, we show how to modify their algorithm in order to get and prove exact solutions and, at the sa...

BACKGROUND The three delays model proposes that maternal mortality is associated with delays in: 1) deciding to seek care; 2) reaching the healthcare facility; and 3) receiving care. Previously, the majority of women who died were reported to have experienced type 1 and 2 delays. With increased coverage of healthcare services, we sought to explore the relative contribution of each type of delay...

Tissue plasminogen activator, a serine protease encoded by the PLAT gene is present in the trabecular meshwork (TM) and other ocular tissues and has been reported to be downregulated by treatment with steroids in vitro. Steroids are known to cause changes in outflow facility of aqueous humor in many species. In the present study, we tested whether overexpression of PLAT can prevent and/or rever...

OBJECTIVE Victimization by and perpetration of domestic violence are associated with co-occurring mental and substance use disorders. METHODS This study used data from the National Survey of Substance Abuse Treatment Services to examine differences in organizational factors, treatment approaches offered, and client-level factors among 13,342 substance abuse treatment facilities by whether or ...

The Primary Casualty Receiving Facility (PCRF) Pathology Department was deployed on Operation GRITROCK from October 2014 to April 2015 to support the medical treatment facility on RFA ARGUS. The department deployed with enhanced microbiology capability and effectively became the microbiology reference laboratory for the Joint Operations Area (JOA). A platelet apheresis capability was delivered ...