It is well known by specialists and others that traumatic brain injury (TBI) is the main cause of death in young people under 40 years old and, at the same time, represents the cause of approximately two-thirds of post-traumatic deaths. Data from the World Health Organization show that 11,5 million Europeans who have survived traumatic brain injuries currently present physical disabilities or c...

Traumatic brain and spinal cord injuries are severe burdens for the patients, their relatives, the health care providers and society as a whole. Recent data demonstrate the magnitude of the problem: It is mostly a disease of the young gen-eration (age 20-45 years) with mortality rates for severe traumatic brain injury (TBI) between 40-50%. In approximately 60% of cases, multiple trauma is accom...

objective(s) cytokines such as il-1β are involved in inflammatory responses. this study evaluated the role of two different kinds of drugs (ibuprofen and celecoxib) on brain il-10 and il-1β after traumatic brain injury (tbi) in male rats. materials and methods rats were assigned into 6 groups: intact, sham, tbi, and treated rats with vehicle, celecoxib or iboprophen. cytokine concentrations wer...

emotion regulation difficulties are from the factors that caused the incidents and automobile accidents and work related. this study aimed to comparing emotion regulation difficulties in mild traumatic brain injury (tbi) patients and normal people in kashan.the study was performed on 30 tbi patients referred to shahid beheshti hospital in kashan city and 30 normal people in kashan. tbi patients...

background: accidents are the second reason for mortality and morbidity in iran. among them, brain injuries are the most important damage. clarification of the effects of brain injuries on different body systems will help physicians to prioritize their treatment strategies. in this study, the effect of pure brain trauma on the cardiovascular system and lungs 24 hours post trauma was assessed. m...

Introduction: Traumatic brain injury (TBI) is still a major health problem in the world. It might cause long-term disability that affect socio-economic life and become nation burden. Post-traumatic cerebral edema develop commit to an unfavorable prognosis. Aquaporin 4 (AQP4) water channel protein key regulator of metabolism brain. Although mechanism AQP4 regulation post-traumatic remains contro...

AIMS Traumatic brain injury (TBI) occurs when the head is impacted by an external force causing either a closed or penetrating head injury through a direct or accelerating impact. In laboratory research, most of the TBI animal models focus on a specific region to cause brain injury, but traumatic injuries in patients do not always impact the same brain regions. The aim of this study was to exam...

Traumatic brain injury (TBI) is an important public health issue as these high-rate mechanical insults to tissue, even on a mild scale, progress secondary cascades that prolong and augment the injury. More effective models are vital study mechanism progression. Although oligodendrocyte progenitor cells (OPCs) mature oligodendrocytes (OLs) have been shown play large role in TBI recovery, researc...

Traumatic brain injury (TBI) occurs suddenly and has damaging effects to the brain that are dependent on the severity of insult. Symptoms can be mild, moderate, or severe. Oxidative damage is associated with traumatic brain injury through reactive oxygen/nitrogen species production. One such species, peroxynitrite, is elevated in TBI brain tissue (Orihara et al. [2001] Forensic Sci. Int. 123:14...

Traumatic brain injury (TBI) affects over 1.5 million Americans annually and consumes a significant amount of healthcare dollars. Identification of complications and factors that impact recovery from TBI is important in improving outcome and allocating appropriate resources. Understanding the role of non-neurologic complications such as sepsis, acute kidney injury, and respiratory problems on T...