The vertebrate brain is regionalized during development into forebrain, midbrain and hindbrain. Fibroblast growth factor 8 (FGF8) is expressed in the midbrain/hindbrain boundary (MHB) and functions as an organizer molecule. Previous studies demonstrated that the brain of basal chordates or ascidians is also regionalized at least into fore/midbrain and hindbrain. To better understand the ascidia...

Homeobox-containing transcription factors crucially regulate the patterning and regionalization of the developing nervous system, as well as the proliferation, survival and differentiation of distinct neuronal populations. Altered expression of these factors markedly impacts the structure and function of the embryonic and adult central nervous system (CNS). In both humans and mice, mutations of...

The water resource literature documents the solution that community water system regionalization (CWSR) offers, based on economies of scale, to challenges small community water systems (CWSs) face born of financial distress. But in practice very few systems actually regionalize. Imposing a model based on economies of scale, this paper estimates stakeholder implications to consumers and water pu...

The research on land cover and its changing value to the ecology environment ecosystem service is of great importance. Understanding landscape patterns accuracy in remote sensing data from multiple sources under eco-regionalization important for relevant eco-regionalization. Land use different ecological regionalization contexts influence massive processes a global scale, many models are depend...

Localized ecological interactions can generate striking large-scale spatial patterns in ecosystems through spatial self-organization. Possible mechanisms include oscillating consumer-resource interactions, localized disturbance-recovery processes and scale-dependent feedback. Despite abundant theoretical literature, studies revealing spatial self-organization in real ecosystems are limited. Rec...

The ability of Gaussian noise to induce ordered states in dynamical systems is here presented in an overview of the main stochastic mechanisms able to generate spatial patterns. These mechanisms involve: (i) a deterministic local dynamics term, accounting for the local rate of variation of the field variable, (ii) a noise component (additive or multiplicative) accounting for the unavoidable env...

A common analogy is to compare regionalization to a train. In the classic tradition, you first decide where you want to go and the best way to get there, given available resources and technology. Second, you design the train to fit with the job that lies ahead. Third, you build the train along with the tracks and then get it moving. The other provinces have all built trains and are moving them ...

The effects of a high-velocity impact on the microstructure, phase transformation and mechanical property of aged Ti49Ni51 alloy are investigated. The transformation behavior and microstructure along the impact direction after impact emerge with regionalization characteristics, including a deformed region near the crater (0-4 mm) and an un-deformed region of the distal crater (5-6 mm). Stress-i...

and Unintentional Firearm Deaths Name: __________________________ Date: _____/_____/_____ 1. How might the possibility that “. . . where there are more guns parents care less about their children’s welfare. . . .” influence the inference one can reach from Dr. Miller’s study? 2. Why did Dr. Miller “. . . control for state level of poverty, urbanization and regionalization”? 3. How does Dr. Mill...

Since its inception in the 1980s, the Home Oxygen Program in British Columbia was centrally managed by the Ministry of Health. Initially a small program with few clients across the province, it soon became a large program with many clients and increasing expenditures. A pilot program started in Victoria (British Columbia) in 1996 demonstrated that managing the program locally could offer better...