Using stress sensitive FRET sensors we have measured cytoskeletal stresses in α-actinin and the associated reorganization of the actin cytoskeleton in cells subjected to chronic shear stress. We show that long-term shear stress reduces the average actinin stress and this effect is reversible with removal of flow. The flow-induced changes in cytoskeletal stresses are found to be dynamic, involvi...

Genetic material always remains at the risk of spontaneous or induced damage which challenges the normal functioning of DNA molecule, thus, DNA repair is vital to protect the organisms against genetic damage. Helicases, the unique molecular motors, are emerged as prospective molecules to engineer stress tolerance in plants and are involved in nucleic acid metabolism including DNA repair. The re...

12 We report on laboratory experiments designed to investigate the effect of 13 dynamic stressing on permeability of fractured rock. Berea sandstone samples 14 were fractured in-situ under triaxial stresses of 10's of MPa, and deionized 15 water was forced through the incipient fracture under conditions of steady and 16 oscillating pore pressure. We find that dynamic stresses produced by pore 1...

C-Jun amino terminal kinase/stress-activated protein kinases (JNK/SAPK) and p38 subgroups of mitogen-activated protein kinases have been suggested to play a critical role in apoptosis, cell growth, and/or differentiation. We found that a short exposure of SKT6 cells, which respond to erythropoietin (Epo) and induce erythroid differentiation, to osmotic or heat shock induced transient activation...

C-Jun amino terminal kinase/stress-activated protein kinases (JNK/SAPK) and p38 subgroups of mitogen-activated protein kinases have been suggested to play a critical role in apoptosis, cell growth, and/or differentiation. We found that a short exposure of SKT6 cells, which respond to erythropoietin (Epo) and induce erythroid differentiation, to osmotic or heat shock induced transient activation...

A bidirectional transient voltage suppressor (TVS) Zener diode was fabricated with abrupt junctions using the low-temperature epitaxy process. The effects of various electrostatic discharge (ESD) stresses on the electrical properties are demonstrated, such as the current­voltage (I­V) and 1/f noise power spectral density (PSD). Very sharp and uniform bidirectional multi-junctions result in good...

[1] This study deals with deformation of small pores in wet soils of relatively high bulk density such as in the final settlement phase of tilled or disturbed soils. Pore deformation was modeled by volume reduction of spherical voids embedded in a homogenous soil matrix. External constant stress and overburden were considered as steady stresses because the change in interaggregate contact stres...

Abstract The main aim of this article is to develop a new boundary element method (BEM) algorithm model and simulate the nonlinear thermal stresses problems in micropolar functionally graded anisotropic (FGA) composites with temperature-dependent properties. Some inside points are chosen treat terms domain integrals. An integral formulation which based on use Kirchhoff transformation firstly us...

Abstract Duplex steel is an austenitic-femtic alloy commonly used in the offshore and subsea oil gas industry. provides a unique combination of good mechanical properties corrosion resistance sweet sour hydrocarbon environment, as well seawater. However, tensile loading, post-weld residual stresses, cathodic protection other factors related to implementation significantly increase probability h...