background: beta thalassemia is a common inherited disease, resulting from one or more of 200 different mutations in the beta-globin gene. qazvin province has attracted migrations of several different populations due to industrialization during the past five decades. the aim of this study was to define the molecular spectrum of beta-thalassemia mutations in qazvin province.   methods: ethylen d...

introduction: thalassemia is common in iran. appropriate therapy for this disease includes a regular blood transfusion and chelation therapy. however, patients will inevitably confront with side effects, particularly iron overloads in critical organ including heart, ductless glands and liver. this study tries to determine the prevalence of diabetes mellitus in transfusion dependent β thalassemi...

objective: thalassemic patients are at risk of zinc deficiency due to various causes including desferal injection, hyperzincuria, high ferritin levels, and hepatic iron overload. we evaluate the effect of zinc supplementation on linear growth of beta-thalassemia patients. methods: one-hundred beta-thalassemic major patients whose heights were within 3rd to l0th percentile were randomly divided ...

abstract background multiple transfusions in thalassemia patients may lead to antibody production against blood group antigens and hemolytic transfusion reaction might occur. in this study, antibody screening test was performed by tube and gel methods to determine the prevalence and specificity of alloantibodies in thalassemia patients. materials and methods in this cross-sectional study, overa...

In times of escalating health-care cost, it is of great importance to carefully assess the cost-effectiveness and appropriateness of the most resource-consuming health interventions. A long-standing and common clinical practice that has been underestimated in cost and overestimated in effectiveness is the transfusion of allogeneic blood products. Studies show that this intervention comes with l...