conclusions abnormal transaminases and uric acid levels are seen in ahf patients. increased ast levels may be a predictor of the need for inotrope during hospital course in these patients. patients and methods a total of 100 patients (aged 16 - 90 years, 60% men) admitted with ahf were enrolled. lfts and uric acid levels were assessed on first day and before discharge, and patients were followe...

Gene duplication is one of the major evolutionary mechanisms providing raw material for the generation of genes with new or modified functions. The yeast Saccharomyces cerevisiae originated after an allopolyploidization event, which involved mating between two different ancestral yeast species. ScALT1 and ScALT2 codify proteins with 65% identity, which were proposed to be paralogous alanine tra...

Chiral amines are a common feature of many active pharmaceutical ingredients. The synthesis very small chiral is particularly challenging, even via biocatalytic routes, as the level discrimination between similarly sized R-groups must be exceptional, yet their creates attractive building blocks that may then used to prepare diverse compounds in further steps. Herein, one smallest amines, 2-amin...

The alterations in serum pseudo-cholinesterase, transaminases, and aldolase observed in 12 agricultural workers exposed to the organo-phosphorus insecticide, malathion, over a period of six months are recorded. A comparison with a series of unselected controls and a series of manual workers is made. Evidence is produced that the majority of the agricultural workers have been suffering from mino...

Intestinal ischaemia typically presents with signs suggestive of an acute surgical abdomen. A raised serum lactate may substantiate the diagnosis. The first case of ischaemic hepatitis mimicking intestinal ischaemia is reported. The recognition of markedly deranged transaminases allows the clinician to differentiate the two diagnoses and potentially avoid the risks incurred with laparotomy.