Malignant small bowel obstruction (MSBO) that does not resolve with conservative measures frequently leaves few treatment options other than palliative care. This single-institution retrospective study assesses the outcomes of a more aggressive approach-concurrent systemic chemotherapy and total parenteral nutrition (TPN)-in the treatment of MSBO. The MD Anderson pharmacy database was queried t...

INTRODUCTION The diagnosis and classification of fistulas based on anatomy, physiology and etiological criteria is the first important stage, conservative treatment consists on patient's stabilization. Finally, on complicated cases, when spontaneous closure fails, specific surgical approach should be applied. CASE PRESENTATION A 50 years-old women patient underwent four surgical interventions...

In 1957, San Pietro and Lang (1) observed that isolated spinach chloroplasts cause a light-stimulated exchange of the hydrogen of water with the hydrogen at the p position of the nicotinamide ring of oxidized TPN and DPN. Their results showed that there are enzymes in chloroplasts which cause activation of both steric positions of the reduced pyridine nucleotides. Since these early studies, it ...

To study the mechanism of the intrahepatic cholestasis observed during total parenteral nutrition (TPN) in neonates, we examined the localization of IgA, secretory component (SC) and complement component C3 (C3) in the liver in 4 patients by light and electron microscopic immunohistochemistry. In the patients who received TPN for 1 month, IgA- and SC-positive cholestasis was limited to bile can...

Introduction Short bowel syndrome (SBS) is defined as intestinal failure due to a loss of intestine resulting in inadequate length of bowel for maintaining the nutrition and hydration of the individual without either intravenous or oral supplementation. With some reported exceptions, the minimum length of small bowel required for infant survival on enteral feeds is generally 25 cm in the presen...

The benefits of early enteral feeding (EEN) have been demonstrated in gastrointestinal surgery. But, the impact of EEN has not been elucidated yet. We assessed the postoperative nutritional status of patients who had undergone pancreaticoduodenectomy (PD) according to the postoperative nutritional method and compared the clinical outcomes of two methods. A prospective randomized trial was under...

Carnitine is a vitamin-like compound that plays important roles in fatty acid β-oxidation and the control of the mitochondrial coenzyme A/acetyl-CoA ratio. However, carnitine is not added to ordinary enteral nutrition or total parenteral nutrition. In this study, we determined the serum carnitine concentrations in subjects receiving ordinary enteral nutrition (EN) or total parenteral nutrition ...

Introduction: Total parenteral nutrition (TPN) is a kind of nutritional support indicated for patients whose clinical situation makes it impossible to cover their nutritional requirements enterally. Despite the fact that TPN is a safe and effective therapy, some complications have been described. One of the most frequent is hypertriglyceridemia. The etiology of this metabolic complication is co...

H i H amilton et al. (1) reported some very interesting and important findings in their article “Default-Mode and TaskPositive Network Activity in Major Depressive Disorder: Implications for Adaptive and Maladaptive Rumination.” In the article, the authors explored dominance of the default-mode network (DMN) over the task-positive network (TPN) and how that dominance might be related to depress...

BACKGROUND/PURPOSE This report describes our experiences with 5 cases of biliary atresia associated with meconium peritonitis caused by perforation of small bowel atresia. METHODS A review of medical records was undertaken in an effort to recognize cases of biliary atresia associated with meconium peritonitis. RESULTS Five patients of 171 with biliary atresia (2.9%) were detected to have me...