drilling operations are exposed to a variety of hazards, some of which may be location and activity dependent and each could pose different risk from different paths.  drilling operation may be vulnerable to hurricanes in one region and be exposed to geohazards in another. however, there are other hazards, (e.g. corrosion, age degradation, poor maintenance), which equally affects every rig. ide...

Safety evaluations for chemicals which possess the ability to cause sensitization by skin contact have traditionally been done using an ad hoc comparative risk assessment technique. Recently, several papers have been published supporting the use of an alternative, and potentially better, quantitative risk assessment approach. While they represent a relatively new approach to risk assessment for...

BACKGROUND This study defined the risk of serious toxicity in phase I trials of molecularly targeted agents (MTA). PATIENTS AND METHODS A retrospective analysis of toxicity data from patients treated in phase I trials of MTAs was carried out to define the rate of treatment-related grade 3/4 toxic effects, deaths and risk factors associated with grade 3 or more toxicity. RESULTS Data from 68...

Despite advances in clinical practice, local anaesthetic systemic toxicity continues to occur with the therapeutic use of anaesthesia. Patterns presentation have evolved over recent years due part increasing ultrasound which has been demonstrated reduce risk. Onset is increasingly delayed, a greater proportion reports are secondary fascial plane blocks, and cases where non-anaesthetist provider...

BACKGROUND Published criteria defining the accelerated phase in chronic myeloid leukemia are heterogeneous and little is known about predictors of poor outcome. METHODS This is a retrospective study of 139 subjects in the accelerated phase of chronic myeloid leukemia treated with imatinib at a single center in Brazil. The objective was to identify risk factors for survival, major cytogenetic ...

PURPOSE Concurrent chemoradiotherapy (CCRT) for squamous cell carcinoma of the head and neck (SCCHN) increases both local tumor control and toxicity. This study evaluates clinical factors that are associated with and might predict severe late toxicity after CCRT. METHODS Patients were analyzed from a subset of three previously reported Radiation Therapy Oncology Group (RTOG) trials of CCRT fo...

background chronic kidney disease (ckd) is a prevalent, progressive, and treatable disease. however, lack of enough data about its prevalence in iran is a major obstacle for its early detection. in order to determine the prevalence of the disease in the country, it is necessary to conduct epidemiologic studies especially on populations with ethnic diversity; hence, this study aimed at determini...

background: musculoskeletal symptoms are the main cause of loss of working time, and increase in labor costs. poor posture is the most important risk factor for work-related musculoskeletal symptoms. this study aimed at evaluating the role of ergonomic risk factors in different surgical (open surgery, laparoscopy, and microsurgery) in the frequency or resonance frequency of musculoskeletal symp...

background : this study was designed to investigate whether there was an association between abo blood groups and car­diovascular risk factors in healthy population. methods : in this cross-sectional study, risk factors screening for cardiovascular disease(cvd) on 5000 healthy persons of go­lestan province, northern iran, in 2005 was estimated by a questionnaire that included age, sex, physical...

objective the purpose of this study was to determine the prevalence and the most common risk factors of motor developmental delay in infants. materials & methods following ethical approval, a study was carried out on the prevalence and risk factors of infants with motor developmental delay. the first stage was conducted through a cross-sectional study to determine the prevalence of motor develo...