Hepatocellular carcinoma is one of the most common cancers in the world, and it is influenced by agents such as DEN, 2-AAF, phenobarbital, alcohol, aflatoxin B1 metabolite or hepatitis viruses (B and C). Oxidative stress is becoming recognized as a key factor in the progression of hepatocarcinogenesis. Reactive oxygen species can play a leading role in initiation and promotion of hepatic carcin...

suppression of cell mediated immunity. Aflatoxins were detected more commonly in urine from users in The Netherlands than from those in ,Merseyside. Aflatoxin B1, the most toxic aflatoxin, was detected in eight specimens from The Netherlands but only one from Merseyside; the most common aflatoxin detected in the specimens from Merseyside was aflatoxin MI, a less toxic derivative of B1. These va...

The rapid regenerative response of the rat liver to partial hepatectomy is associated with a decline in liver epidermal growth factor receptor numbers which implies that ligand epidermal growth factor receptor interactions maybe important in initiating and/or modulating this process. The proliferative process in toxic hepatitis (where in contrast with partial hepatectomy the majority of hepatoc...

OBJECTIVES To illustrate the close association between a disturbed psychosocial up-bringing, frequent physical illness, and medical interventions. METHOD We report a case of a 44-year-old woman with anorexia nervosa (AN) and Sheehan's syndrome who died as a result of a toxic cardiac arrest. RESULTS The patient presented with a BMI of 13.6 kg/m(2). She refused any intensive-care treatment an...

The term “hepatitis viruses” refers to a diverse group of viruses all of which have the human liver as the primary target of replication and give rise to hepatitis or inflammation of the liver. Their replication may result in mass destruction of liver cells. Consequences include failure of the liver to fulfil basic functions such as removal of bilirubin from the circulatory blood system. Biliru...

Abstract. The search for new strategies the correction of exogenous toxic liver lesions is due to steady increase in incidence hepatitis and cirrhosis among working population, which an important medical social problem.
 aim determine effect cryopreserved placenta extract (CEP) on state rats with tetrachloromethane (CCl4)-induced damage by indicators lipid peroxidation (LP) markers cytolys...

Fulminant hepatic failure, a life threatening condition induced by massive hepatocellular necrosis may be associated with significant morbidity and mortality. A better understanding of the pathophysiology of this condition, associated with advances in intensive care management and liver transplantation have improved outcomes. This review describes recent advances in the management of fulminant ...

Background: The incidence of chronic liver disease is increasing worldwide. Common causes include alcohol, hepatitis B and C non-alcoholic fatty (NAFLD). Abnormalities in hematological parameters are common patients with cirrhosis. There paucity data geriatric population diseases.Methods: A pre-structured performa was prepared to collect the demographic that included Age, Gender, Occupation, Ar...

Nowadays viral hepatitis is one of the most common and important causes of chronic liver disorders in the world. Extrahepatic manifestations of viral hepatitis consist a main part of the disease. The main viruses causing hepatitis include Hepatitis A, B and C viruses. Herein common skin manifestations in hepatitis C virus (HCV) are discussed. Chronic hepatitis causes skin disorders both directl...