Induction of c-fos in the spinal cord due to pain is well established. This study aims to look at the effects of acute swim stress on Fos-like immunoreactivity (FLI) induced by formalin and how it is modulated by ketamine and morphine. Acutely-stressed and non-stressed adult male Sprague Dawley rats were pretreated with intraperitoneal injection of ketamine 5 mg/kg (Ketava, Atlantic Lab), morph...

heat stress is a major environmental stress limiting wheat productivity in most cereal growing areas of the world. in order to map and characterize quantitative trait loci controlling heat tolerance, 144 recombinant inbred lines deriving from the cross of kauz and mtrwa116 were assessed in a greenhouse and growth chamber at 35°c. one hundred and sixty six ssr and 3 aflp markers were used to...

Acute toxicity of commercial grade organophosphate insecticide, quinalphos (25% emulsified concentration) to common carp (Cyprinus carpio) was tested through bioassay. The acute toxicity of quinalphos to the fingerlings exposed for 96 hr was found to be 2.75 ppm. For sub lethal toxicity study, the fish were exposed to two concentration viz., 1/10th of LC50 (0.275 ppm) and 1/5th of LC50 (0.55 pp...

Tolerance to morphine analgesia following repeated administration disturbs the continuation of opioid therapy for severe pain. Emerging evidence suggests that the development of morphine tolerance may be antagonized by painful stimuli. To clarify the detailed mechanisms of these phenomena, we examined the effects of several pain stimuli on morphine-induced tolerance. Subcutaneous (s.c.) injecti...

Global declines in amphibians likely have multiple causes, including widespread pesticide use. Our knowledge of pesticide effects on amphibians is largely limited to short-term (4-d) toxicity tests conducted under highly artificial conditions to determine lethal concentrations (LC50). We found that if we used slightly longer exposure times (10-16 d), low concentrations of the pesticide carbaryl...

This study was conducted to determine the effects of acute swim stress on the pain behavior response and c-Fos expression in the rat spinal cord. Male Sprague-Dawley rats weighing 250-300g were divided into four groups consisting of rats subjected to acute swim stress (S), formalin injection (F), acute swim stress with formalin injection (S+F) and control rat (C) (n=6 per groups). Rats were acu...