OBJECTIVE To evaluate the association of environmental exposure to tobacco smoke from husbands and from work, as well as from family members in early life, with all cause mortality and mortality due to cancer or cardiovascular disease in Chinese women. DESIGN Ongoing prospective cohort study in Shanghai, China. PARTICIPANTS Of 72,829 women who had never smoked, 65,180 women provided informa...

The aim of the study was to assess the effect of residential radon exposure on the risk of lung cancer in never-smokers and to ascertain if environmental tobacco smoke modifies the effect of residential radon. We designed a multicentre hospital-based case-control study in a radon-prone area (Galicia, Spain). All participants were never-smokers. Cases had an anatomopathologically confirmed prima...

Smoking is a risk factor for lung diseases, including chronic obstructive pulmonary disease and lung cancer. However, the molecular mechanisms mediating the progression of these diseases remain unclear. Therefore, we sought to identify signaling pathways activated by tobacco-smoke exposure, by analyzing nuclear phosphoprotein expression using phosphoproteomic analysis of lung tissue from mice e...

Sins of the Father ParentalSmoking and Childhood Cancer Exposure to passive (or environmental) tobacco smoke has been implicated in numerous childhood ailments ranging from low birth weight to middle ear disease. Passive smoke has also been suspected, but not proven, to increase the risk of childhood cancer. Clarifying this issue is crucial not only for the protection of children's health but a...

Smoking prevalence in remote Australian Aboriginal communities remains extraordinarily high, with rates reported of up to 82%. Widespread exposure to environmental tobacco smoke (ETS) is exacerbated by overcrowded housing. Implementation of existing smoke-free policies is challenged by the normalization of smoking and a lack of appropriate regulation resources. This paper celebrates a grassroot...

OBJECTIVE To determine whether exposure to environmental tobacco smoke was associated with oxidative stress among patients hospitalised for acute myocardial infarction. DESIGN An existing cohort study of 1,261 patients hospitalised for acute myocardial infarction. SETTING Nine acute hospitals in Scotland. PARTICIPANTS Sixty never smokers who had been exposed to environmental tobacco smoke...

1,3-Butadiene (BD) is a smoke component selected by the World Health Organization (WHO) study group on Tobacco Product Regulation (TobReg) for mandated lowering. We examined the tobacco smoke-related health effects induced by BD and possible health impacts of risk reduction strategies. BD levels in mainstream smoke (MSS) from international and Canadian cigarettes and environmental tobacco smoke...

CONTEXT Electronic cigarettes (e-cigarettes) have earned considerable attention recently as an alternative to smoking tobacco, but uncertainties about their impact on health and indoor air quality have resulted in proposals for bans on indoor e-cigarette use. OBJECTIVE To assess potential health impacts relating to the use of e-cigarettes, a series of studies were conducted using e-cigarettes...

Exposure to tobacco smoke during pregnancy is associated with a range of adverse outcomes in offspring, including cognitive deficits and increased incidence of attention deficit-hyperactivity disorder, but there is a considerable controversy with regard to the causal role of tobacco smoke in these outcomes. To determine whether developmental exposure to the primary psychoactive ingredient in to...

Sins of the Father ParentalSmoking and Childhood Cancer Exposure to passive (or environmental) tobacco smoke has been implicated in numerous childhood ailments ranging from low birth weight to middle ear disease. Passive smoke has also been suspected, but not proven, to increase the risk of childhood cancer. Clarifying this issue is crucial not only for the protection of children's health but a...