نتایج جستجو برای: tna

تعداد نتایج: 313  

Journal: :Journal of bacteriology 2009
Rui Yang Luis R Cruz-Vera Charles Yanofsky

Distinct features of the ribosomal peptide exit tunnel are known to be essential for recognition of specific amino acids of a nascent peptidyl-tRNA. Thus, a tryptophan residue at position 12 of the peptidyl-tRNA TnaC-tRNA(Pro) leads to the creation of a free tryptophan binding site within the ribosome at which bound tryptophan inhibits normal ribosome functions. The ribosomal processes that are...

Journal: :Vaccine 2015
Phillip R Pittman Ronald B Reisler Changhong Y Lindsey Fernando Güereña Robert Rivard Denise P Clizbe Matthew Chambers Sarah Norris Leonard A Smith

Ricin is a potent toxin and potential bioterrorism weapon for which no specific licensed countermeasures are available. We report the safety and immunogenicity of the ricin vaccine RVEc™ in a Phase 1 (N=30) multiple-dose, open-label, non-placebo-controlled, dose-escalating (20, 50, and 100μg), single-center study. Each subject in the 20- and 50-μg dose groups (n=10 for each group) received thre...

Journal: :Acta Physiologica 2021

Aim Hypoxia-inducible factors (HIFs) are O2-sensitive transcription that regulate multiple biological processes which essential for cellular adaptation to hypoxia. Small molecule inhibitors of HIF-prolyl hydroxylase domain (PHD) dioxygenases (HIF-PHIs) activate HIF-dependent transcriptional programs and have broad clinical potential. HIF-PHIs currently in global late-stage development the treat...

Journal: :AJNR. American journal of neuroradiology 2007
M C Gustafsson O Dahlqvist J Jaworski P Lundberg A-M E Landtblom

BACKGROUND AND PURPOSE Spectroscopic studies (1H-MR spectroscopy) of normal-appearing white matter (NAWM) in patients with multiple sclerosis (MS) with MR imaging brain lesions have already been performed, but our intention was to investigate NAWM in MS patients who lack brain lesions to elucidate whether the same pathologic changes could be identified. MATERIALS AND METHODS We checked 350 me...

Journal: :Hypertension 2003
William J Welch Margarida Mendonca Shakil Aslam Christopher S Wilcox

The spontaneously hypertensive rat (SHR) exhibits angiotensin II (Ang II)-dependent oxidative stress and reduced efficiency of renal oxygen usage (QO2) for tubular sodium transport (TNa). We tested the hypothesis that oxidative stress determines the reduced TNa:QO2 ratio in the clipped kidney of the early 2-kidney, 1-clip (2K,1C) Ang II-dependent model. One week after sham operation (Sham) or c...

Journal: :The Journal of antimicrobial chemotherapy 2013
S García-Cobos M Arroyo J Campos M Pérez-Vázquez B Aracil E Cercenado B Orden N Lara J Oteo

OBJECTIVES To determine the mechanisms of resistance to β-lactam antibiotics in clinical isolates of Haemophilus parainfluenzae. METHODS Twenty clinical isolates of H. parainfluenzae with decreased susceptibility to aminopenicillins were examined and compared with a control group of 20 fully susceptible isolates. In this collection, the presence of amino acid substitutions in the transpeptida...

Journal: :Environmental Research Letters 2023

Abstract In recent decades, temperature variations have significantly affected the ecosystem and human livelihood in Pakistan. The wavelet analysis is employed to identify associations between regional change global teleconnections, i.e. Atlantic Multidecadal Oscillation (AMO), Arctic (AO), North (NAO), El Niño–Southern (ENSO), Pacific Decadal (PDO), Tropical Northern Index (TNA), Pacific/North...

2006
Pieter T. Visscher

Marine methylotrophic bacteria that consumed methyl bromide (MeBr) and/or dunethyl sulfide (DMS) were isolated: 4 strains from Long Island Sound, USA (LIS) and 1 from the tropical North Atlantic (TNA). Substrates used for enrichment were DMS, trimethylarnine (TMA) or TMA plus MeBr. Attempts to obtain isolates on MeBr as the sole source of carbon and energy were unsuccessful. Three of the isolat...

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