نتایج جستجو برای: tissue expression
تعداد نتایج: 1613066 فیلتر نتایج به سال:
Background & Aims: Common nutritional mistakes cause inflammation and homeostasis disruption in heart cells. Inflammasome complex is one of the pathways that induces inflammation and degradation of cardiac protein regeneration. The aim of the present study was to investigate changes in NLRP1inflammasome, PI3k, apoptosis, and histopathology of heart tissue following aerobic physical activity and...
Introduction: Obesity causes accumulation of proinflammatory factors in adipose tissue and it is regarded as a risk factor for diabetes and cardiovascular diseases. Aerobic exercise increases insulin sensitivityand reduces fat accumulation and proinflammatory factors. The present study aimed to investigate the effect of endurance exercise on resistin gene expression as one of the proinfammatory...
Background and Objectives: Taking morphine can cause damage to the hippocampus. Oleuropein has a protective effect on brain neurons. The aim of this study was to determine the effect of oleuropein on brain-derived neurotrophic factor (BDNF) protein expression level in hippocampal tissue and memory defect induced by morphine in rats. Materials and Methods: In this experimental study, 40 male Wi...
Background & objective: Breast cancer is the leading cause of cancer related death in females. Sphingosine kinase 1 (SPHK1) and its product sphingosine-1-phosphate (S1P) are the essential key regulator molecules in breast cancer through their ability to promote cell proliferation, angiogenesis, cell proliferation, and lymphagiogenesis. SPHK1 i...
Objective(s): Lapachone is a natural naphthoquinone-derived compound found in Tabebuia avellanedae. It is well-known for its analgesic, anti-inflammatory, anti-microbial, diuretic, and anti-cancerous effects. However, the wound-healing effects of this compound are not known yet. The aim of this study was to investigate the wound healing activity of naphthoquinones (α-l...
Introduction & Objective: Gastric cancer is one of the most common cancers in Iran, and in some regions, the prevalence of this cancer is the highest among all diagnosed cancers, also it has the highest mortality rate. Concerning to different tumoral mutations that have role in prognosis and type of treatments in different cancers, this study was done to determine the association between p53 ...
background: in cancers of prostate, breast, oropharynx, lung, hypopharynx and skin, human tissue kallikreins has been demonstrated as a main role in these problems. there are many research works in which some human tissue kallikreins are expressed in salivary glands. in the present study, the main goal was to determine expression of human tissue kallikreins 4, 8, 10, 11 and 13 in pleomorphic ad...
Background & Objective: To study the immunophenotype of prostate cancer (PC) with the presence and absence of intraluminal inclusions (IIn), depending on the grade score. Methods: A total of 30 PC samples with IIn (group E) and 30 PC samples without them (group C) were studied. These groups were divided into 2 subgroups, depending on the grade of malignan...
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