Standard UICC crocidolite fibres and fibres extracted from occupationally exposed human lung tissue have been analysed by scanninng electron microscopy after different preparation procedures. A significant fibre loss has been shown due to the adhesion of fibres to the breakers. Fibres are also discarded during the washing and extraction of the lung tissue samples. The recovery was found to be 3...

OBJECTIVE To determine whether autologously transferred human adipose tissue maintains viability in vivo for prolonged periods. DESIGN Six healthy female patients (mean age, 61.5 years; mean body mass index, 23.4 kg/m2) received autologous fat transplants from the gluteus to the nasolabial folds. Subcutaneous fat was sampled from facial and gluteal sites 4 times in 1 year. SETTING Private p...

Any effective cancer therapy developed to date is associated with a spectrum of normal tissue effects of varying incidence and severity. With an increasing number of novel therapeutic approaches undergoing clinical testing and an increased effort to optimize the established treatment modalities, methods for reliable quantification of normal tissue effects have become a key element in advancing ...

Breast cancer is a complex and heterogeneous disease. In spite of the advances made in recent decades, a better understanding of the intrinsic mechanisms of this disease is crucial. The development of new biomarkers is absolutely necessary to improve diagnosis and prognosis. Research using the proteomic approach has generated interesting results; however, the complexity of the mammary glan...

This paper deals with the torsional moment depending on the angle of torsion of the compact bone in laboratory animals and humans. Based on the data from laboratory animals, obtained by measurement, the data on dependence of the torsional moment and the angle of torsion were assumed for humans. Measurements were carried out on four groups of compact bone in laboratory animals. One was the contr...

Taphonomic processes affecting bone post mortem are important in forensic, archaeological and palaeontological investigations. In this study, the application of tissue microarray (TMA) analysis to a sample of femoral bone specimens from 20 exhumed individuals of known period of burial and age at death is described. TMA allows multiplexing of subsamples, permitting standardized comparative analy...

The identification of glandular tissue in breast X-rays (mammograms) is important both in assessing asymmetry between left and right breasts, and in estimating the radiation risk associated with mammographic screening. The appearance of glandular tissue in mammograms is highly variable, ranging from sparse streaks to dense blobs. Fatty regions are generally smooth and dark. Texture analysis pro...

Featured Article: Carr TP, Andresen CJ, Rudel LL. Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts. Clin Biochem 1993;26:39 – 42. The need to measure serum or plasma cholesterol prompted the development of enzyme-based colorimetric assays during the 1970s. These assays eventually replaced the traditional chemical methods. The advantages o...

OBJECTIVES Proteome analysis has emerged as a promising strategy to the identification of potential biomarkers and to further confirm the importance of certain pathways in the schizophrenia (SCZ) pathophysiology. Reviewing the results of 13 proteome studies in SCZ brain tissue, we aimed to provide information regarding potential proteins biomarkers as well as information about the pathophysiolo...

background and aim: iron overload in patients with thalassemia major is one of the most important complications of this disease and its cardiac complications are the most important causes of death in these patients.mri t2 is the perfect device to assess the amount of iron deposited in the heart of thalassemia patients, but it causes waste of time and also is an expensive diagnostic method. tiss...