Primary hyperparathyroidism due to parathyroid adenomas may be associated with ectopic parathyroid gland localization in 20-25% of the patients. We report herein the excision of an ectopic parathyroid adenoma which was detected in the thymus gland by gamma probe intraoperatively. A 38-year-old patient presented to our clinic with a history of bilateral nephrolithiasis, chronic hypercalcaemia, a...

Carcinoma showing thymus-like differentiation (CASTLE) is a rare malignancy that occurs in the soft tissues of the neck or in the thyroid gland. When it occurs in the thyroid, it is difficult to differentiate from thyroid tumor. Here, we report such a case. A 34-year-old man presented with a mass in the left lower neck in August 1999. Thyroid ultrasonography showed a hypoechoic mass, which repl...

GCM proteins constitute a small transcription factor family with a DNA-binding domain exhibiting a novel fold composed of two subdomains rigidly held together by coordination of one of two structural zinc cations. In all known cases, GCM proteins exert the role of master regulators: the prototypical family member determines gliogenesis in Drosophila melanogaster, whereas mammalian GCM proteins ...

An anterior mediastinal tumor was detected in a 45-year-old female during a medical checkup. Chest computed tomography (CT) showed the anterior mediastinal tumor and a pulmonary tumor in the right lower lobe. Furthermore, tumors of the parathyroid gland, pancreas, and pituitary gland were also detected. She was clinically diagnosed with multiple endocrine neoplasia type1 (MEN1). The patient und...

GCM proteins constitute a small transcription factor family with a DNA-binding domain exhibiting a novel fold composed of two subdomains rigidly held together by coordination of one of two structural zinc cations. In all known cases, GCM proteins exert the role of master regulators: the prototypical family member determines gliogenesis in Drosophila melanogaster , whereas mammalian GCM proteins...

The thymus is critical in establishing and maintaining the appropriate microenvironment for promoting the development and selection of T cells. The function and structure of the thymus gland has been extensively studied, particularly as the thymus serves an important physiological role in the lymphatic system. Numerous studies have investigated the morphological features of thymic involution. R...

In previous papers I have shown that feeding thymus gland to the larvae of salamanders retards or completely inhibits metamorphosis 1'~ as well as growth. 3 I t was also demonstrated ~ that the inhibition of both growth and metamorphosis is not caused by specific growthinhibiting substances contained in the thymus, but by a deficiency of the thymus in certain substances which are necessary for ...