نتایج جستجو برای: thrombopoietin receptor

تعداد نتایج: 591318  

2015
Monica Carpenedo Silvia Cantoni Veronica Coccini Marilena Fedele Enrica Morra Enrico Maria Pogliani

Thrombopoietin mimetics are new treatment options for patients with immune throm-bocytopenia (ITP). Because of their mechanism of action, long-term administration was envisioned in order to maintain effective thrombopoiesis. We report on 30 romiplostim treated patients: 13/27 responders (48%) achieved stable platelet counts on a mean romiplostim dose of 2.43 µg/kg and were able to stop romiplos...

Journal: :Haematologica 1998
A Koşar I C Haznedaroglu Y Büyükaşik O Ozcebe S Kírazli S Dündar

Circulating thrombopoietin and interleukin-6 concentrations were investigated in two different settings of thrombocytopenia. Twenty patients with autoimmune thrombocytopenic purpura (ATP), 12 patients with aplastic anemia (AA) and 15 healthy subjects were studied. Thrombopoietin was significantly increased in AA and deficient in ATP. Interleukin-6 was significantly increased in ATP, compared to...

Journal: :American journal of hematology 2012
James N George

Management of adults with primary immune thrombocytopenia (ITP) has changed dramatically in the past 10 years. New regimens of corticosteroids for first-line treatment have been introduced and are currently being evaluated in a randomized clinical trial. Many patients may not have durable remissions with initial corticosteroid regimens and may require additional, second-line, treatment. For the...

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