Associate models are powerful tools for large software ecosystem orchestrators to manage clusters within its ecosystem. At present, however, it remains unclear how these associate models are used in practice and of what elements such models consist. Without an overview of what associate models consist of, the concept of software ecosystem orchestration will remain elusive. In this paper, a conc...

Host genotype may be closely related to the different outcomes of Hepatitis B virus (HBV) infection. To identify the association of variants and HBV infection, we comprehensively investigated the cytokine- and immune-related gene mutations in patients with HBV associated hepatocellular carcinoma (HBV-HCC). Fifty-three HBV-HCC patients, 53 self-healing cases (SH) with HBV infection history and 5...

[1] There is growing interest in the application of ‘‘continuous simulation’’ conceptual rainfall-runoff models for flood frequency estimation as an adjunct to event-based or statistical design methodology. The approach has advantages that stem from the use of models with continuous water balance accounting. Conceptual rainfall-runoff models usually require calibration, which in turn requires g...

Hepatitis B virus (HBV) infection is a universal health problem and may result into acute, fulminant, chronic hepatitis liver cirrhosis, or hepatocellular carcinoma. Sequence for protein X of HBV was retrieved from Uniprot database. ProtParam from ExPAsy server was used to investigate the physicochemical properties of the protein. Homology modeling was carried out using Phyre2 server, and refin...

BACKGROUND Hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) is a major global health problem. A few risk calculators have been developed using mainly HBV seromarkers as predictors. However, serum HBV DNA level, HBV genotype, and mutants are not routinely checked in regular health examinations. This study aimed to assess the predictability of HCC risk in chronic hepatitis B patient...

By bioluminescence imaging and hydrodynamic gene transfer technology, the activities of hepatitis B virus (HBV) promoters and the effects of HBV enhancers on these promoters in mice under true physiological conditions have been assessed. Our studies reveal that either of the two HBV enhancers can stimulate HBV major promoter activity in hepa 1-6 cells (in vitro) and in mouse liver (in vivo), an...

Abstract. Hydrological catchment models are important tools that commonly used as the basis for water resource management planning. In 1960s and 1970s, development of several relatively simple to simulate runoff started, a number so-called conceptual (or bucket-type) were suggested. these models, complex heterogeneous hydrological processes in represented by limited storage elements fluxes betw...

The aim of this study was to determine the prevalence and the incidence of hepatitis B virus (HBV) among haemodialysis (HD) subjects and to evaluate whether testing for serological markers at the time of admission is suitable for HBV screening in this population. One hundred twenty-three patients belonging to two HD centres from São Paulo, Brazil, were tested prospectively. HBV DNA was detected...

Background & Aims HBV genotype G (HBV/G) is mainly found in co-infections with other genotypes and was identified as an independent risk factor for liver fibrosis. This study aimed to analyse the prevalence of HBV/G healthy European carriers characterize crosstalk genotypes. Methods A total 560 were tested via HBV/G-specific PCR co-infections. Quasispecies distribution analysed deep sequencing,...