Polymorphonuclear neutrophils' chemotaxis, surface charge, superoxide anions generation, NBT (nitro blue tetrazolium) reduction and intracellular lysozyme, and beta-glucuronidase content were estimated in patients with type I diabetes mellitus in a similar state of metabolic control. The chemotaxis of diabetic cells toward bacterial chemotactic factors was similar to controls, whereas migration...

In this report we describe a new technique for the measurement of region at risk after coronary artery ligation in the rabbit by NADH fluorophotography. We also describe the application of this technique to a study of nifedipine combined with reperfusion in experimental myocardial infarction. In 16 untreated rabbits the epicardial surface area of NADH fluorescence immediately after coronary lig...

AIM The use of dexamethasone (DEX) in mesenchymal cell culture induces osteoblastic differentiation and, consequently, formation of mineralized tissues. Tissue engineering proposes the development of therapeutic strategies aimed at structural and functional regeneration of biological tissues. In this sense, cell characterization in vitro is critical to ensure the development of such techniques....

Colorectal cancer is one of the most diagnosed cancers in world. KRAS mutations colon are being responsible for progressiveness and resistance standard therapeutic available. Marine sponge sources chemotherapy. Stylissa carteri a marine that lives Indonesia its anti-cancer effects starting to be explored nowadays. The purpose this study was determine cytotoxicity anti-proliferative effect ethan...

background: nanoparticles have become one of the leading technologies over the past two years. the extensive use of nanoparticles has raised great concern about their occupational fate and biological effects. with an increase in the production and use of nanomaterial, it is more likely to get exposed to them occupationally and environmentally. objective: to assess the toxicity of silver nanopar...

The results of recent studies demonstrating the presence pro-inflammatory mediators in osteoarthritis (OA), as well known similarity histological signs inflammation rheumatoid arthritis (RA) and OA, suggest an important role NETosis immune OA patients. Our objective was to assess ability blood neutrophils from ОA patients generate spontaneously after vitro induction, impact reactive synovitis o...

The dehydrogenase activity in mycobacteria is a promising field of research for the following reasons. Youmans et al. (1955, 1957) showed that small particles, containing dehydrogenases and possessing characteristics of mitochondria, stimulate in mice the production of a degree of immunity which is equal to the immunity produced by a 1-mg quantity of whole living cells of H37Ra. On the other ha...

Abstract Introduction Glutaminolysis, beside glycolysis, is a key metabolic pathway of cancer cell that provides energy and substrates for the synthesis nucleic acids, proteins, lipids. The mediated by both mitochondrial cytosolic enzymes. Neither expression glutaminolysis enzymes in colon cells nor influence various oxygen concentrations on their has been studied so far. Objectives aim study w...