indandione 1 was brominated to yield 2-bromoindandione 2 which on further reacted with substituted thiocarbamides, carbamides, 2-aminothiophenols, 2-aminophenol and triazoles to furnished 3-substituted aniline-2-thia-4-aza-6,7-benzo-8-oxo-bicyclo [3.3.0]-1(5),3-octadiene 3, 3-substituted aniline-2-oxa-4-aza-6,7-benzo-8-oxo-bicyclo [3.3.0]-1(5),3-octadiene 4, 2-thia-5-aza-9-oxo-3,4-(3’-substitut...

Objective: Many methods can be found in literature for the synthesis a Oxazines and Thiazines. Few are reported one-pot multi component cyclo-condensation of an alkayane urea / Thiourea Aldehyde to 2- amino-4H-1, 3-Oxazines or Different catalysts like Trifluoro-acetic acid, glacial acetic acid under reflux condition Mandal Co-workers have utilized perchloric (HClO4) supported on silica gel as c...