background and aims: influenza vaccination is one of the best way to prevent and control influenza worldwide. it is manufactured by who-licensed companies based on the who expertise committee annually. the aim of this study was partial quality control of the commercial human influenza vaccine 2008-9 and its matching with the circulating strains. materials and methods: the trivalent imported vac...

mercury is one of the three major environmental metal poisons, and mercuric chloride is a highly reactive compound which can harm cells by a variety of mechanisms including direct interaction with sulphydryl groups of proteins and enzymes, therefore affecting the enzymatic activity. this study focused on the effect of hg++ on horseradish peroxidase (donor: hydrogen peroxide oxidoreductase, ec 1...

the aim of the present work was to purify cysteine protease inhibitors from rapeseed (brassica napus l.), with potential activity on digestive protease of colorado potato beetle (cpb), leptinotarsa decemlineata (say). ammonium sulfate precipitated proteinaceous fractions; 30, 50, 70, and 100% showed 39.07, 57.03, 51.47, and 22.44% inhibition on the fourth instar larval gut general protease acti...

introduction: executive functions, including inhibition and flexibility are important for many of human behavior. hence, emphasis has led to interventions to improved executive function. the aim of this study was examination of impact of cognitive inhibition training on flexibility performance of student with learning disability. materials and methods: the design of this study was a pretest-pos...

neural mass models are computational nonlinear models that simulate the activity of a population of neurons as an average neuron, in such a way that different inhibitory post synaptic potential (ipsp) and excitatory post synaptic potential (epsp) signals could be reproduced. these models have been developed either to simulate the recognized neural mechanisms or to predict some physiological fac...

A short oligodeoxynucleotide (ODN) with 2-(1H)-pyrimidinone at the HhaI DNA methyltransferase target site (GCGC) is shown to induce a level of inhibition of methyl transfer and thermal stability of the complex with the enzyme identical to that achieved with a similar ODN substituted with 5-azacytosine. The drugs responsible for these effects-zebularine and 5-azacytidine/2'-deoxy-5-azacytidine-a...

Kelulut honey (KH) has a broad spectrum of antibacterial effects that conceivably deteriorate upon heat treatment. However, further synergistic combinations with plant extract might be value in improving the bactericidal capacity. Therefore, this study reports on combination KH Phyllanthus niruri as both are independently known to bactericidal. P.niruri was incorporated into 2 types KH; untreat...

A full account of the total syntheses of proteasome inhibitors TMC-95A and -B is provided. A key feature of the syntheses involved installation of a cis-propenylamide moiety by a thermal rearrangement of an alpha-silylallyl amide. The scope and mechanism of the enamide-forming reaction are discussed. Also provided are some preliminary results from SAR studies. It was found that simplified analo...

the geothermal phenomena in the area nearby the euganean hills (near padua, in italy) areknown and exploited for therapeutic purposes since ancient times, and recently also for aesthetic purposes.this paper presents the first characterization of the radionuclides content in the euganean thermal waters and mud, extended to a great number of spas. in particular the radionuclides content of both t...