DNA transposition is central to the propagation of temperate phage Mu. A long-standing problem in Mu biology has been the mechanism by which the linear genome of an infecting phage, which is linked at both ends to DNA acquired from a previous host, integrates into the new host chromosome. If Mu were to use its well-established cointegrate mechanism for integration (single-strand nicks at Mu end...

Background The meaningful use (MU) of electronic medical records (EMRs) is being implemented in three stages. Key objectives of stage one include electronic analysis of data entered into structured fields, using decision-support tools (e.g., checking drug-drug interactions [DDI]) and electronic information exchange. Objective The authors assessed the performance of medical students on 10 stage-...

The widespread use of the maize Mutator (Mu) system to generate mutants exploits the preference of Mu transposons to insert into genic regions. However, little is known about the specificity of Mu insertions within genes. Analysis of 79 independently isolated Mu-induced alleles at the gl8 locus established that at least 75 contain Mu insertions. Analysis of the terminal inverted repeats (TIRs) ...

The Mu transposon of maize exists in a highly mutagenic strain called Robertson's Mutator. Plants of this strain contain 10-50 copies of the Mu element, whereas most maize strains and other plants have none. When Mutator plants are crossed to plants of the inbred line 1S2P, which does not have copies of Mu, the progeny plants have approximately the same number of Mu sequences as did their Mutat...

‎a $mu$-way $(v,k,t)$ $trade$ of volume $m$ consists of $mu$‎ ‎disjoint collections $t_1$‎, ‎$t_2‎, ‎dots t_{mu}$‎, ‎each of $m$‎ ‎blocks‎, ‎such that for every $t$-subset of $v$-set $v$ the number of‎ ‎blocks containing this t-subset is the same in each $t_i (1leq‎ ‎i leq mu)$‎. ‎in other words any pair of collections ${t_i,t_j}$‎, ‎$1leq i< j leq mu‎$ is a $(v,k,t)$ trade of volume $m$. in th...

For the development of phage therapy, systematic understanding mechanisms of bacteriophage resistance will be required. We describe a new strain of Escherichia coli O157:H7, named Mu(L), which stably co-exists with the O157:H7-specific lytic bacteriophage PP01. Chemostat cultures of E. coli O157:H7 infected with PP01 showed unchanging cell concentration, but phage concentrations which increased...