The in vitro activity of CEM-101, a new fluoroketolide, was determined against Gram-positive organisms with various macrolide susceptibility profiles. Experiments for determination of the MICs and minimum bactericidal concentrations (MBCs), timed killing, single-step and multistep mutation rates, the erythromycin induction of resistance, postantibiotic effect (PAE), and drug interactions were p...

A Simple and efficient method for synthesis of tetrahydropyrimido[4,5-b]quinoline derivatives via three component reaction of aromatic aldehydes, dimedone and 6-amino uracil derivatives using a catalytic amount of sulfonic acid functionalized nanoporous silica (SBA-15-Pr-SO3H) is described. The advantages of this method are easy and clean work-up, high yield, mild reaction c...

the objective of this research was to study the biological activities of various extracts and the chemical composition of the essential oil trigonella monantha c. a. mey. subsp. monantha by gas chromatography (gc) and gas chromatography-mass spectroscopy (gc-ms), from the compounds derived from the aerial parts. the overall results of t. monantha tests allow us to conclude various extracts [hex...

abstract: essential oils are commonly used to treat minor health problems. in this study the chemical compositions of lavandula officinalis and thymus vulgaris were determined by gas chromatography and mass spectrometry. gc/ms analysis of t. vulgaris resulted in thymol as the major oil component where as methyl sulfony exhibited as the most abundant constituent of l. officinalis. the antibacter...

background: according to the recent studies, the antibacterial activities of silver nanoparticles (ag-nps) were studied on gram-positive staphylococcus aureus and gram-negative escherichia coli. in this study antibacterial effect of silver nanoparticles that used for coating textiles, on e.coli and s.aureus was investigated. methods: silver nanoparticles were coated on textile fabric by corona ...

background: in recent years, plants natural products have gained considerable attention as natural preservers for use in different industries. due to their free radical scavenging activities, phenolic compounds can prevent a wide range of diseases such as cancers and cardiovascular and neurodegenerative diseases. for a long time, different ferulago species have been in use as medicinal plants w...

Phytochemical investigations of Piper sarmentosum Roxb., yielded four compounds; three amides, identified as 3-(3’,4’,5’-trimethoxyphenylpropanoyl) pyrrolidine, 3-(4’-methoxyphenylpropanoyl) pyrrole, N -(3-phenylpropanoyl) pyrrole and a sterol namely β -sitosterol . 3-(4’-Methoxyphenylpropanoyl) pyrrole was found for the first time in this Piper spe...