BACKGROUND The purpose of this study was to evaluate the antinociceptive effect of black raspberry (Rubus occidentalis) fruit extract (ROE) in a rat model of chronic muscle pain and examine the mechanisms involved. METHODS Adult male Sprague-Dawley rats were used, and chronic muscle pain was induced by two injections of acidic saline into one gastrocnemius muscle. For the first experiment, 50...

BACKGROUND The UVB and heat rekindling (UVB/HR) model shows potential as a translatable inflammatory pain model. However, the occurrence of central sensitization in this model, a fundamental mechanism underlying chronic pain, has been debated. Face, construct and predictive validity are key requisites of animal models; electromyogram (EMG) recordings were utilized to objectively demonstrate val...

Abstract. Hydrological time series (HTS) are the key basis of water conservancy project planning and construction. However, under influence climate change, human activities other factors, consistency HTS has been destroyed cannot meet requirements mathematical statistics. Series division wavelet transform effective methods to reuse analyse HTS. they limited by change-point detection mother (MWT...

The prevalence of obstructive sleep apnea (OSA) among professional truck drivers has varied from 28 to 78% in previous studies. In this study we wanted estimate the OSA and with both subjectively measured sleepiness objectively ability stay awake (ie syndrome, OSAS) Finland. Altogether 2066 received a structured questionnaire. 175 had clinical examination laboratory studies, which included resp...

The issue of physical rehabilitation post-COVID patients stays relevant up to this day. Most publications discuss inpatient and only few describe outpatient such patients. aim . Our study was performed investigate efficacy with lung injury. Methods This a prospective non-randomized open controlled study. All COVID-19-associated injury were referred supervised program. We analyzed 6-minute walk ...

OBJECTIVE We aimed to evaluate the feasibility and short-term efficacy of endobronchial treatment with one-way valves for giant emphysematous bulla in surgically unfit patients. METHODS Nine consecutive patients with giant emphysematous bulla were enrolled in the last 3 years. Endobronchial valves were placed in the segmental bronchi to functionally isolate the airway that supplied the bulla,...

A multi-proxy approach was used to examine the geomorphic dynamics and environmental history of an upper deltaic floodplain tract in the Sacramento-San Joaquin Delta, California. Three long cores were collected from the McCormack-Williamson Tract (MWT) and these cores were analyzed for bulk density, loss-on-ignition, fine (clay and silt) content, Al concentration, magnetic susceptibility, polle...

INTRODUCTION Pulmonary rehabilitation has been demonstrated to improve exercise capacity, dyspnoea, quality of life and to reduce the adverse effects of acute exacerbations. Current guidelines recommend exercise training in patients with mild to very severe disease. However, there is insufficient data comparing the efficacy of different training approaches and intensities. METHODS Between Jan...

Objective(s): A novel IQ-SPECTTM method has become widely used in clinical studies. The present study compares the quality of myocardial perfusion images (MPI) acquired using the IQ-SPECTTM (IQ-mode),conventional (180° apart: C-mode) and L-mode (90° apart: L-mode) systems. We assessed spatial resolution, image reproducibility and quantifiability using various physical phantoms. Materials and Me...