BACKGROUND β-thalassemia is the most common hereditary disease in Iran and more than 2 million carriers of the β-thalassemia mutant gene are living in this country. OBJECTIVE To determine pregnancy outcome of women with β-thalassemia minor. MATERIALS AND METHODS In this retrospective, case-control study in two universities affiliated hospitals in Shiraz, all pregnancies occurred between 200...

The present study was carried out to evaluate the effectiveness of NESTROFT as a screening test for β-thalassemia trait. Naked Eye Single Tube Red cell Osmotic Fragility Test [NESTROFT] is an uncumbersome and inexpensive test for the detection of βthalassemia. NESTROFT was applied to 150 patients of β-thalassemia trait and 150 normal control samples. The test was successful in detecting 143 sub...

Latar Belakang: Pandemi coronavirus disease 2019 (COVID-19) yang disebabkan oleh virus SARS-CoV-2 di awal tahun 2020 menyebabkan Pembatasan Sosial Berskala Besar (PSBB) Kota Palembang. Hal ini kemungkinan memengaruhi kesempatan penderita thalassemia untuk melakukan kontrol teratur dan mendapat transfusi darah karena rumah sakit rujukan sebagian besar terletak Palembang.Tujuan: Untuk mengetahui ...

BACKGROUND: Thalassemia is a genetic blood disorder and has not been cured. children need special attention from the family as one of efforts in treating with thalassemia depends on coping strategies owned by family. AIM: This research aimed to discover deeply explore caring for major aged 6–12 years. METHODS: study used quantitative qualitative approaches (mixed methods). For we total sampling...

Even the life span has prolonged for the last 40 years, increase in frequently seen complications with increasing age negatively affect the life quality of thalassemia patients. In our study, complications encountered in 67 ß-thalassemia patients who were followedup at our hospital between 1 January 2004 and 31 May 2009 were retrospectively analyzed. Fifty-six patients were followed up with dia...

OBJECTIVES A health-promoting lifestyle (HPL) is a factor that affects the quality of life (QoL) in patients with beta-thalassemia (β-thalassemia). Due to the lack of studies of this issue, this study aimed to determine the association between HPL and QoL among adults with β-thalassemia. METHODS This cross-sectional (descriptive-analytic) study was conducted among 389 adult patients with β-th...

The present study was conducted in the Outpatient Department (OPD) of Yangon Children's Hospital (YCH) during June to November 1990 to determine the hematological data of 133 Myanmar patients with thalassemia trait who were the parents of patients with known beta-thalassemia major or hemoglobin E (Hb E)/beta-thalassemia. The mean values of hemoglobin (Hb) concentration, packed cell volume (PCV)...

BACKGROUND Thalassemia is the most common monogenic disease in South-East of Iran. Despite the 70% reduction in Iranian thalassemia cases after thalassemia control comprehensive program, 601 affected babies were born in Sistan and Balouchistan Province, Iran from 2002 to 2010, so this study aims at investigating the causes of new thalassemia cases. METHODS Data from this retrospective cross-s...

BACKGROUND Due to the tropism of human parvovirus B19 to erythroid progenitor cells, infection in patients with an underlying hemolytic disorder such as beta-thalassemia major leads to suppression of erythrocyte formation, referred to as transient aplasia crisis (TAC), which may be life-threatening. We investigated the prevalence of parvovirus B19 among patients with beta thalassemia major atte...

Globin synthesis studies are useful in the analysis of thalassemia syndromes. We have applied globin synthesis and free a-chain pool studies of peripheral blood to characterize hematologic disorders where aor thalassemia was present in combination with HbS or HbC. In 60 nonthalassemic controls, the $/a specific activity ratio was 1.O ± 0.06 (SD). In three patients with HbS-fi#{176}-thalassemia,...