Background and Objective: Teucrium polium (TP) has shown hypoglycemic effect in type 1 diabetes induced by single high dose of the cytotoxic agent streptozotocin (STZ) in rats. This study was conducted to evaluate whether its aqueous extract could have such an effect in multiple low-dose STZ-induced model of type 1 diabetes in rats. Materials and Methods: Male Wistar rats were divided into cont...

Introduction Reactive oxygen species (ROS) have been shown to play a critical role in many diseases such as diabetes mellitus, cancer, Alzheimer, arteriosclerosis and other conditions. Chronic glucose levels in blood or cells of diabetic patients are known to cause oxidative damages, followed by an increasing in ROS production and/or dysfunction of antioxidant defense system (enzyme or non-enzy...

UNLABELLED A growing body of evidence indicates that specific phytochemicals can increase an efficacy of cancer chemotherapy. AIM To evaluate promoting effect of the methanolic extract of Teucrium Polium (Me-TP) on cytotoxic and apoptotic activity of anticancer drugs of vinblastine, vincristine and doxorubicin in vitro. METHODS Skmel-3, Saos-2, SW480, MCF-7, KB, EJ and A431 cell lines were ...

Teucrium polium L. (Labiatae) has long been recognized in folk medicine in the treatment of many pathophysiological implications, such as gastrointestinal disorders, inflammations, diabetes and rheumatism. In this study antimicrobial activity of two crude extracts obtained from Teucrium polium L. was tested against bacterial species. Minimum Inhibitory Concentration (MIC) and Minimum Bactericid...

In the present study, protective effect of Teucrium polium L. (Labiatae) extract on acetaminophen-induced hepatotoxicity was investigated in mice. Animals were divided into six groups, each group consist of 8 mice. Group one as the negative control group received normal saline, while group two received only crude extract of T. polium L. (500 mg/Kg) for five days and group three as the positive ...