background :reproductive endocrine disorders and sexual dysfunction are common among men with epilepsy. we investigated sexual hormone serum levels among men with newly diagnosed epilepsy, before starting any antiepileptic drug (aed), and then after starting carbamazepine (cbz), to determine the role and effects of epilepsy versus cbz in creating reproductive endocrine disorders.   methods : in...

Background: Smoking is a global problem that negatively affects human health and fertility the endocrine functions of male reproductive system. Objectives: The present study aims to investigate influence different types tobacco smoking (cigarette, hookah, electronic) on semen parameters sex hormones in males from Gaza Strip. Methods Materials: A total 206 samples were classified into 156 cases ...

The effects of exposure to chemical weapons containing sulfur mustards on the serum levels of total and free testosterone. gonadotropins and prolactin was investigated in young Iranian men. In the first five weeks after injury both serum total and free testosterone were significantly decreased as compared to control values. Three of 13 men had total testosterone below 300 ng/dL and two of ...

BACKGROUND Spinal cord injury (SCI) causes infertility in male patients through erectile dysfunction, ejaculatory dysfunction, semen and hormone abnormalities. Oxidative stress (OS) is involved in poor semen quality and subsequent infertility in males with SCI. The aim of this study is to examine the effects of SCI on the level of testosterone hormone. MATERIALS AND METHODS In this experiment...

The immunocompetence handicap hypothesis (ICHH) suggests that the male sex hormone testosterone has a dual effect; it controls the development and expression of male sexually selected signals, and it suppresses the immune system. Therefore only high quality males are able to fully express secondary sexual traits because only they can tolerate the immunosuppressive qualities of testosterone. A m...

OBJECTIVE Hormone receptor-positive breast cancers respond favorably to subcutaneous testosterone combined with an aromatase inhibitor. However, the effect of testosterone combined with an aromatase inhibitor on tumor response to chemotherapy was unknown. This study investigated the effect of testosterone-letrozole implants on breast cancer tumor response before and during neoadjuvant chemother...

The precise impact of age-related changes in hormone levels on cognition in men is still unclear due to differing study designs and contradictory findings. This study was undertaken to examine the relationship between endogenous sex hormone levels and cognitive functioning in healthy older men using a comprehensive battery of neuropsychological tests and measurement of serum sex hormone levels....

Objective: three major strategies have been tested for combating the losses in muscle mass and strength that accompany ageing. Those strategies are testosterone replacement for men, growth hormone replacement and resistance exercise training. This review will cover the risks and benefits associated with each of these interventions. Methods: searches of PubMed and Web of Science through May 2004...

Primary or secondary hypogonadism results in a range of signs and symptoms that compromise quality of life and requires life-long testosterone replacement therapy. In this study, an implantable nanochannel system is investigated as an alternative delivery strategy for the long-term sustained and constant release of testosterone. In vitro release tests are performed using a dissolution set up, w...

Mất đoạn AZF trên nhiễm sắc thể Y là nguyên nhân gây vô sinh quan trọng ở nam giới. Mối liên giữa mất với nồng độ hormone sản và các đặc điểm lâm sàng bệnh vấn đề cần được làm sáng tỏ. Mục tiêu: khảo sát Y, dục mối một số thiểu tinh tinh. Đối tượng phương pháp nghiên cứu: chúng tôi cứu 161 Kết quả: gặp 15 (chiếm 9,3%), trong đó AZFc hay nhất. Nồng FSH, LH testosterone trung bình lần lượt là: 16...