BACKGROUND In numerous Caudata, the testis is known to differentiate new lobes at adulthood, leading to a multiple testis. The Iberian ribbed newt Pleurodeles waltl has been studied extensively as a model for sex determination and differentiation. However, the evolution of its testis after metamorphosis is poorly documented. METHODS Testes were obtained from Pleurodeles waltl of different age...

Ectopic testis predisposes to a high risk of germ cell tumor development. Treatment of advanced testicular germ cell tumor developing in an uncorrected abdominal testis is based on primary chemotherapy followed by removal of the testis along with residual masses. However, persistence of viable tumor particularly in the testis is always noted since testis penetration of chemotherapeutic agents i...

An case of torsion of the appendix of testis is described in a 10 years old boy. He presented with sudden onset of severe pain in the left testis of 3 days duration. Emergency exploration of the left testis revealed a gangrenous appendix of the left testis. The appendix of the testis was excised and the wound was closed. The patient made a smooth post-operative recovery.

The Sox family plays essential roles as transcription factors in vertebrates; however, little is known about the Lutraria sieboldii. L. sieboldii are pleasant to eat with a short growth cycle and have become one of best bottom-seeded enrichment species Guang Xi. In this study, Sox2 (named LsSox2) Sox9 LsSox9) from were cloned, their expression patterns analyzed. length LsSox2 gene coding sequen...

YY super-males have rarely been detected in nature and only been artificially created in some fish species including tilapia and yellow catfish (Pelteobagrusfulvidraco), which provides a promising model for testis development and spermatogenesis. In our previous study, significant differences in morphology and miRNA expression were detected between XY and YY testis of yellow catfish. Here, sole...

busulfan, a cytotoxic drug, which is currently used as a chemotherapeutic agent, has many side effects on different body organs. in this research, the effects of busulfan on sperm parameters and microstructure of mouse testis were investigated. methods: busulfan was injected intrapretoneally at 10, 20, 30, 40 and 50 mg/kg and testes were removed after 4, 6 and 8 weeks, weighed and processed for...

BACKGROUND Abnormal fetal testis development can result in disorders of sex development (DSDs) and predispose to later testicular dysgenesis syndrome (TDS) disorders such as testicular germ cell tumours. Studies of human fetal testis development are hampered by the lack of appropriate model, and intervention systems. We hypothesized that human fetal testis xenografts can recapitulate normal dev...

Hydrocele testis is an accumulation of clear fluid between the tunica vaginalis (Pic. 1) and testis (Pic. 2). Adult-onset primary non-communicating hydrocele testis causes progressive swelling and local discomfort on the affected side of the scrotum, and this has been attributed to the enhanced secretion and defective absorption of fluid in the space between the tunica vaginalis and testis. The...

OBJECTIVE To discuss the relationship between testicular microlithiasis and testis tumors in children and to consider the chances of testis preserving surgery in specific cases. CASE DESCRIPTION Pre-adolescent presenting testicular microlithiasis and a larger left testis, corresponding to a cystic testicular tumor. The tumor was excised, with ipsilateral testis preservation. Histology diagnos...