نتایج جستجو برای: tenecteplase
تعداد نتایج: 297 فیلتر نتایج به سال:
In eukaryotic cells, polypeptides are N glycosylated after passing through the membrane of the ER into the ER lumen. This modification is effected cotranslationally by the multimeric oligosaccharyltransferase (OST) enzyme. Here, we report the first cross-linking of an OST subunit to a nascent chain that is undergoing translocation through, or integration into, the ER membrane. A photoreactive p...
BACKGROUND A catheter-based approach after fibrinolysis is recommended if fibrinolysis is likely to be successful in patients with acute ST-elevation myocardial infarction. We designed a 2x2 randomized, open-label, multicenter trial to evaluate the efficacy and safety of the paclitaxel-eluting stent and tirofiban administered after fibrinolysis but before catheterization to optimize the results...
Abstract Background Stroke thombolysis has been a proven effective treatment for acute stroke since 1995. Since then Alteplase the standard thrombolytic agent used in hyperacute patient, dose being decided by body weight (0.9mg/kg). 10% of is given as bolus, and remaining 90% an infusion. As based, more than one vial can be required. Tenecteplase recent agent, 2017 large multi-centre randomised...
BACKGROUND AND PURPOSE Thrombolysis >4.5 hours after ischemic stroke onset is unproven. We assessed the feasibility of tenecteplase (TNK) treatment in patients with evidence of an ischemic penumbra 4.5 to 24 hours after onset. METHODS Acute ischemic stroke patients underwent perfusion computed tomography (CT)/magnetic resonance imaging. Patients with cerebral blood volume (CBV) or diffusion w...
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