Tendon pathology has many manifestations, from spontaneous rupture to chronic tendinitis or tendinosis; the etiology and pathology of each are very different, and poorly understood. Tendon is a comparatively poorly vascularised tissue that relies heavily upon synovial fluid diffusion to provide nutrition. During tendon injury, as with damage to any tissue, there is a requirement for cell infilt...

As tendon stem/progenitor cells were reported to be rare in tendon tissues, tendons as vulnerable targets of sports injury possess poor self-repair capability. Human ESCs (hESCs) represent a promising approach to tendon regeneration. But their teno-lineage differentiation strategy has yet to be defined. Here, we report that force combined with the tendon-specific transcription factor scleraxis ...

BACKGROUND Clinical tendon injuries represent serious and unresolved issues of the case on how the injured tendons could be improved based on natural structure and mechanical strength. The aim of this studies the effect of aquatic activities and alogenic platelet rich plasma (PRP) injection in healing Achilles tendons of rats. METHODS Forty rats were randomly divided into 5 equal groups. Seve...

OBJECTIVE To examine the seasonal distribution of tendon ruptures in a large cohort of patients from Vancouver, Canada. DESIGN Retrospective chart review. SETTING Acute Achilles tendon rupture cases that occurred from 1987 to 2010 at an academic hospital in Vancouver, Canada. Information was extracted from an orthopaedic database. PARTICIPANTS No direct contact was made with the participa...

Introduction Degeneration and tearing of rotator cuff tendon causes significant morbidity in our ageing population. While conservative treatment is favored, there are no current drug therapies to specifically treat cuff or other tendon injuries so surgical repairs are common (over 14,000 annually in Australia). Unfortunately half of these repairs fail within 12 months. The poor management optio...

Background: Pain in the shoulder is third-most prevalent musculoskeletal pain type. Most frequently involved tendinopathy/tendon tears supraspinatus tendon, followed by a combination of and infraspinatus tendon. At present, gray-scale ultrasound MRI are used to determine tear size, gross morphology, postsurgical tendon repair. However, they unable material characteristics muscle or Aims Objecti...

Introduction: Radial nerve palsy, a common peripheral injury, significantly impacts the quality of life affected individuals. The standard treatment is tendon transfer, but optimal choice transfers remains subject ongoing debate. This study aimed to evaluate radial palsy through transfer with flexor carpi radialis combination in Bangladeshi population. Methods: observational was conducted over ...

RATIONALE The operative procedure for Achilles tendon rupture is relatively simple, but venous thromboembolism is serious complication with a high incidence after Achilles tendon rupture. However, the guideline for thromboprophylaxis in Achilles tendon rupture is unclear. PATIENT CONCERNS The patient was 32-year-old male and underwent Achilles tendon open repair surgery. He was healthy and th...

Acute simultaneous rupture of the anterior cruciate ligament (ACL) and patellar tendon is a rare injury. We present a case report of a 32-year-old male patient with ruptured ACL and ipsilateral patellar tendon rupture sustained while playing baseball. Surgery was performed on the patellar tendon and the ACL simultaneously. The clinical and radiological outcomes of the treatment were successful....

Simultaneous rupture of both the patellar tendon and the anterior cruciate ligament is a relatively rare injury. Its diagnosis can easily be missed during the initial examination. Treatment options include immediate repair of the patellar tendon with either simultaneous or delayed reconstruction of the ACL. We present the case of a combined rupture of the patellar tendon, the anterior cruciate ...