AIM To investigate the effects of radiotherapy on distraction osteogenesis performed on the same bone in an area that has not received radiation. Radiotherapy (Co60) was carried out in a region where tumors may develop, and then, on the assumption that the tumoral region had been removed, distraction osteogenesis was carried out, and the effects were investigated. METHOD Thirty New Zealand ra...

This paper describes the biological mechanisms of normal tissue reactions after radiation therapy, with reference to conventional treatments, new treatments, and treatments in developing countries. It also describes biological reasons for the latency period before tissue complications arise, the relationship of dose to incidence, the effect of increasing the size of the irradiated volume, early...

PURPOSE The aim of this study was to elucidate the sequence of very early bystander signalling events and to determine the role of the different signalling molecules in both the production of the bystander signal and the response to this signal. MATERIALS AND METHODS Human keratinocytes (HaCaT cell line) were irradiated (0.005, 0.05 and 0.5 Gy) using a cobalt 60 teletherapy unit, the medium w...

PURPOSE The aim of this study was to compare levels of apoptosis, necrosis, mitotic cell death and senescence after treatment with both direct radiation and irradiated cell conditioned medium. MATERIALS AND METHODS Human keratinocytes (HaCaT cell line) were irradiated (0.005, 0.05 and 0.5 Gy) using a cobalt 60 teletherapy unit. For bystander experiments, the medium was harvested from donor Ha...

A 9-year-old boy was referred in July 1982 because of a 4-month history of headache in the frontal area. He had also developed a visual disturbance. The physical examination was normal. The visual field test showed bitemporal hemianopsia and his visual acuity was Vd 0.5 and Vs 0.2. A mild optic nerve atrophy without papilledema was seen in the left optic fundus. Endocrine evaluation demonstrate...

1 \VAL=. J. 11. Carcinoma of thr esophagus Cobalt 60 teletherapy. .-\rr~er 1 Rortzteen.. 9 l : 6 i . 19W. 2 KILLEX. D A,, A\U COLL~SS I1 .4.. Tmcheo-esophageal fishila resr~ltlng frnn, "on-pen~hating tmmrma to the chrsL I . Thor and Cnrdznca~c Surg , j0:lfl.I. 1965. 3 TE~RACOL. 1. *yo S w ~ n . R. H.. Dt~cases of the Esophoprrs. W B. Saunder, Co.. Philadelphla, 1958 1 PAPAIOA~XOC. h 1.: 4 simpl...

Abstract Background Digital health interventions have a potential to improve safety, efficacy and quality of care, reducing waste in healthcare costs. Despite premises, the evidence regarding cost effectiveness digital tools is scarce limited. Objectives: The aim this systematic review summarize on cost-effectiveness assess whether studies meet established criteria. Methods We queried PubMed, S...