Intrathymic T-cell maturation critically depends on the selective expansion of thymocytes expressing a functionally rearranged T-cell receptor (TCR) beta chain. In addition, TCR-independent signals also contribute to normal T-cell development. It is unclear whether and how signals from the 2 types of pathways are integrated. Here, we show that T-cell factor-1 (TCF-1), a nuclear effector of the ...

Contractual date of delivery to the CEC: 31.12.2011 Actual date of delivery to the CEC: 31.12.2011 Project Number and Acronym: 248351 FARAMIR Editor: Berna Sayrac (FT) Authors: Berna Sayrac (FT), Daniel Denkovski (UKIM), Valentin Rakovic (UKIM), Vladimir Atanasovski (UKIM), Liljana Gavrilovska (UKIM), Tao Cai (HWSE), Lorenzo Iacobelli (TCF), Christophe Le Martret (TCF), Ian F. Akyildiz (UPC), J...

This paper proposes a new relationship between thermal conductivity and degree of saturation unsaturated soils, referred to as the function (TCF). The sigmoidal was developed so that all parameters have physical meaning. After calibration model using data from literature comparison with other available TCFs, TCF were related those soil-water retention curves for soils investigated in process. l...

This work investigated the efficiency of a tetraacetylethylenediamine/ hydrogen peroxide/triethanolamine (TAED/H2O2/TEA) system for lowtemperature bleaching of cotton fabric, with and without ultrasonic assistance. The low-temperature bleaching results were compared to those obtained from a conventional H2O2 bleaching system. The application of TAED/H2O2/TEA without ultrasonic assistance to gre...

Deubiquitinating enzymes (DUBs) are involved in the regulation of distinct critical cellular processes. Ubiquitin C-terminal Hydrolase L1 (UCH L1) has been linked to several neurological diseases as well as human cancer, but the physiological targets and the regulation of UCH L1 expression in vivo have been largely unexplored. Here we demonstrate that UCH L1 up-regulates beta-catenin/TCF signal...

T-cell factor/lymphoid enhancer factor (TCF/LEF) transcription factors are the major end point mediators of Wnt/Wingless signaling throughout metazoans. TCF/LEFs are multifunctional proteins that use their sequence-specific DNA-binding and context-dependent interactions to specify which genes will be regulated by Wnts. Much of the work to define their actions has focused on their ability to rep...

Tooth bleaching using peroxide-based materials is an effective procedure in dentistry. Studies provide evidence on the safety of bleaching by dental professionals. However, concerns and controversy remain regarding the safety of bleaching systems that do not involve dental professionals, especially those available at mall kiosks, salons, spas, and cruise ships. Bleaching causes tooth sensitivit...

Today, the bleaching of nonvital, discolored teeth is a low-risk routine treatment for improving esthetics. This review article focuses on the etiology of tooth discolorations, different treatment techniques, and risks of bleaching procedures. Some tooth discolorations in endodontically treated teeth are caused by dental treatments. The three most popular techniques for nonvital tooth bleaching...

During dental bleaching the staining potential of the surface would increase. This study aims to evaluate the staining susceptibility of one bleached composite resin after the exposure to three different beverages: Peruvian purple corn based beverage (chicha morada), green tea, and distilled water. Thirty disk-shaped specimens of one nanofill composite resin were prepared. The specimens were th...