Sleep deprivation has been shown to alter decision-making abilities. The majority of research has utilized fairly complex tasks with the goal of emulating 'real-life' scenarios. Here, we use a Lottery Choice Task (LCT) which assesses risk and ambiguity preference for both decisions involving potential gains and those involving potential losses. We hypothesized that one night of sleep deprivatio...

This study examined the effects of two nights of total sleep deprivation (TSD) and two nights of recovery sleep on response inhibition. Thirty-eight young, healthy adults performed a Go-NoGo task at 14 : 00 after: (1) a normal night of sleep; (2) each of two consecutive nights of TSD; and (3) each of two consecutive nights of recovery sleep; they also performed the task at 05 : 00 during the fi...

Recognition tests are a very popular means of assessing the memory effectiveness of advertisements. Unfortunately the recognition scores obtoined by current methods reflect both the memory for an advertisement and the response biases of the respondents. The outhors introduce the theory of signol detection (TSD) v/hich can be used to secure independent estimates of memory and response bias in re...

Mục tiêu: Đánh giá kết quả việc sử dụng vạt có cuống liền tại chỗ trong che phủ khuyết hổng phần mềm ngón tay Bệnh viện Trung ương Thái Nguyên. Đối tượng và phương pháp nghiên cứu: từ tháng 01 năm 2020 đến 2023 30 được để cho 28 bệnh nhân (BN) khoa Chấn thương chỉnh hình. Có 15 BN nam, 13 nữ, độ tuổi trung bình là 35 (từ 18 60). Thời gian theo dõi tháng. Kết quả: lâm sàng đánh dựa vào sức sống ...

Waren Tay was born in 1843; he qualified in medicine at the London Hospital and was appointed to it as a surgeon. He was also on the staff of the Royal London Ophthalmic Hospital at Moorfields and City Road, and the North East Hospital for Children, which became Queen Elizabeth Hospital, Hackney Road. A versatile man, he was also dermatologist to the Hospital for Diseases of the Skin. In 1881 h...

Tay-Sachs disease (TSD) is the prototype for ethnic-based carrier screening, with a carrier rate of ∼1/27 in Ashkenazi Jews and French Canadians. HexA enzyme analysis is the current gold standard for TSD carrier screening (detection rate ∼98%), but has technical limitations. We compared DNA analysis by next-generation DNA sequencing (NGS) plus an assay for the 7.6 kb deletion to enzyme analysis...

Many recessive genetic disorders are found at a higher incidence in people of Ashkenazi Jewish (AJ) descent than in the general population. The American College of Medical Genetics and the American College of Obstetricians and Gynecologists have recommended that individuals of AJ descent undergo carrier screening for Tay Sachs disease, Canavan disease, familial dysautonomia, mucolipidosis IV, N...

The lysosomal enzyme, @-hexosaminidase, is composed of two chains, a and 8. In Tay-Sachs disease, mutations in the gene encoding the a-chain produce a @-hexosaminidase deficiency that results in the storage of its natural substrate, GMz ganglioside. To obtain the background information for the eventual identification of the mutational errors in Tay-Sachs disease and to determine possible relati...

BACKGROUND GM2 gangliosidosis-AB variants a rare autosomal recessive neurodegenerative disorder occurring due to deficiency of GM2 activator protein resulting from the mutation in GM2A gene. Only seven mutations in nine cases have been reported from different population except India. CASE PRESENTATION Present case is a one year old male born to 3rd degree consanguineous Indian parents from Ma...