1. Byles DB, Frith P, Salmon JF. Anterior uveitis as a side effect of topical brimonidine. Am J Ophthalmol. 2000;130:287-291. 2. Goyal R, Ram AR. Brimonidine tartrate 0.2% (Alphagan) associated granulomatous anterior uveitis. Eye. 2000;14:908-910. 3. Cantor LB. The evolving pharmacotherapeutic profile of brimonidine, an alpha 2-adrenergic agonist, after four years of continuous use. Expert Opin...

In the title compound, {[Ga(2)(C(4)H(4)O(6))(2)(OH)(2)]·2H(2)O}(n), the Ga(III) atom is located on a twofold rotation axis and is six-coordinated by two O atoms from bridging hydroxide groups and four O atoms from two symmetry-related tartrate units in a slightly distorted octa-hedral environment. Each tartrate unit binds to two Ga(III) atoms as a bis-chelating bridging ligand by two pairs of h...

A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of Zolpidem tartrate in bulk and pharmaceutical dosage forms. Zolpidem tartrate shows maximum absorbance at 238.5 nm with molar absorptivity of 4.4648×10lit/mol/cm. Beer’s law was obeyed in the concentration range of 2-16 μg/ml. The limit of detection and limit of quantification were...

An immunochemical method for quantitative analysis of the tartrate-resistant acid phosphatase (EC 3.1.3.2), band 5, is presented. This method involves precipitation of the enzyme from the serum by the antibody specific to band 5 and by sheep anti-rabbit immunoglobulin, followed by analysis of the enzyme activity in the precipitate. The precipitation procedure eliminates the interferences of the...

Under the title " Experimental Studies ill Bilharzia Therapy ($. spindalis)Dr. Hamilton Fairley, in the August 1924 issue of the Indian Medical Gazette, published details of a comparative investigation of the action of antimony tartrate and emetine on goats experimentally infected with 6". spindalis. Dr. Fairley found emetine superior to antimony tartrate as a specific cure for the goats and wr...

Serotyping is not sufficient to differentiate between Salmonella species that cause paratyphoid fever from the strains that cause milder gastroenteritis as these organisms share the same serotype Salmonella Paratyphi B (S. Paratyphi B). Strains causing paratyphoid fever do not ferment d-tartrate and this key feature was used in this study to determine the prevalence of these strains among the c...

Recent cumulative evidence suggests the possibility of predicting the in vivo metabolic clearance and/or hepatic availability (Fh) from in vitro metabolism data under linear conditions. Under nonlinear conditions, however, it is essential to consider the rate constant for the absorption (ka) for predicting Fh after oral administration, because the time profiles for the portal vein concentration...

A cationic bis-imidazolium-based amphiphile was used to form thermoreversible nanostructured supramolecular hydrogels incorporating neutral and cationic drugs for the topical treatment of rosacea. The concentration of the gelator and the type and concentration of the drug incorporated were found to be factors that strongly influenced the gelling temperature, gel-formation period, and overall st...

ment there was no appreciable change in his condition. At this stage my attention was drawn to the case of ' dermatitis exfoliata ' cured by injections of urea-stibamine, reported by Dr. Norrie in the Indian Medical Gazette for March, 1927, p. 142; and to an article on dermal leishmanoid by Dr. B. M. Das Gupta in the April 1927 number of the same journal, p. 199. I accordingly changed the treat...

The kinetics of racemization of meluadrine tartrate in aqueous solution was investigated by HPLC, over the pH range of 1.2 to 12 at 40, 60 and 80 degrees C. The racemization was followed by measuring both the residual (R)-enantiomer and formed (S)-enantiomer of meluadrine. The pH-racemization rate profile of meluadrine showed a minimum racemization rate constant between pH 4 and 6, and the rate...